Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 7/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30890277 | 1.00 | ALDH1A1 (0.52) | ALDH1A1LMNAMAPTTHRBKMT2A | |
| SCHEMBL27404998 | 1.00 | ALDH1A1 (0.52) | ALDH1A1LMNAMAPTTHRBKMT2A | |
| SCHEMBL29536266 | 0.86 | ALDH1A1 (0.68) | ALDH1A1LMNAMAPTTHRBKMT2A | |
| SCHEMBL994347 | 0.86 | ALDH1A1 (0.68) | ALDH1A1LMNAMAPTTHRBKMT2A | |
| SCHEMBL25370697 | 0.86 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPTTHRBKMT2A | |
| SCHEMBL10035920 | 0.86 | ALDH1A1 (0.56) | ALDH1A1LMNAMAPTTHRBKMT2A | |
| SCHEMBL29554755 | 0.86 | ALDH1A1 (0.56) | ALDH1A1LMNAMAPTTHRBKMT2A | |
| SCHEMBL14852226 | 0.85 | MAPT (0.59) | ALDH1A1LMNAMAPTTHRBKMT2A | |
| SCHEMBL30890258 | 0.84 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPTTHRBKMT2A | |
| SCHEMBL31485106 | 0.84 | ALDH1A1 (0.51) | ALDH1A1LMNAMAPTTHRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024108009-A1 | DYRK/CLK PROTACS AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2024-05-23 | — | — | WO | disclosed |