Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 4/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.34 |
| ▸ | RXRA | P19793 | 4/20 | 0.34 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.32 |
| ▸ | BACE1 | P56817 | 3/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30890482 | 0.87 | POLB (0.40) | NR1H2NR1H3RXRAPOLBHSD17B10 | |
| SCHEMBL27244767 | 0.85 | AKR1B1 (0.39) | AKR1B1AKR1B10AKR1A1MAOAMAOB | |
| SCHEMBL30890780 | 0.84 | MAOB (0.34) | AKR1B1AKR1B10AKR1A1MAOAMAOB | |
| SCHEMBL30992283 | 0.83 | CCNB2 (0.36) | NR1H2NR1H3RXRAIMPDH2BACE1 | |
| SCHEMBL30890800 | 0.83 | IMPDH2 (0.30) | IMPDH2 | |
| SCHEMBL30890432 | 0.82 | — | — | |
| SCHEMBL30890471 | 0.81 | NR1H2 (0.41) | NR1H2NR1H3RXRA | |
| SCHEMBL30890440 | 0.80 | NR1H2 (0.35) | NR1H2NR1H3RXRAIMPDH2 | |
| SCHEMBL30992270 | 0.80 | USP30 (0.34) | — | |
| SCHEMBL30890399 | 0.80 | AR (0.32) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612156-A1 | ANTI-VIRAL COMPOUNDS | Aligos Therapeutics, Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| US-20240199647-A1 | ANTI-VIRAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-06-20 | — | — | US | disclosed |
| WO-2024097296-A1 | ANTI-VIRAL COMPOUNDS | ALIGOS THERAPEUTICS, INC. (US) | 2024-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199647-A1 | ANTI-VIRAL COMPOUNDS | EIF2AK2, ZC3HAV1, HAVCR2 | AKR1B1 3356/4885AKR1B10 3482/4885AKR1A1 3324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.