Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 4/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | OTUD7B | Q6GQQ9 | 3/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30890744 | 0.85 | AKR1B1 (0.35) | AKR1B1AKR1B10AKR1A1MAOBMAOA | |
| SCHEMBL30890780 | 0.82 | MAOB (0.34) | AKR1B1AKR1B10AKR1A1KDM4EALDH1A1 | |
| SCHEMBL27244744 | 0.81 | AKR1B1 (0.33) | AKR1B1AKR1B10AKR1A1NR3C2NR3C1 | |
| SCHEMBL27244787 | 0.81 | AKR1B1 (0.31) | AKR1B1AKR1B10AKR1A1NR3C2NR3C1 | |
| SCHEMBL27245042 | 0.81 | AKR1B1 (0.31) | AKR1B1AKR1B10AKR1A1NR3C2NR3C1 | |
| SCHEMBL27244814 | 0.81 | L3MBTL1 (0.33) | AKR1B1NR3C2ALDH1A1KMT2A | |
| SCHEMBL27244692 | 0.81 | AKR1B1 (0.31) | AKR1B1AKR1B10AKR1A1 | |
| SCHEMBL27245205 | 0.78 | TDP1 (0.34) | AKR1B1 | |
| SCHEMBL27245231 | 0.77 | — | — | |
| SCHEMBL27245173 | 0.77 | OTUD7B (0.36) | OTUD7BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199647-A1 | ANTI-VIRAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199647-A1 | ANTI-VIRAL COMPOUNDS | EIF2AK2, ZC3HAV1, HAVCR2 | AKR1B1 3356/4885AKR1B10 3482/4885AKR1A1 3324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.