Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29198813 | 0.94 | LMNA (0.47) | LMNAHPGDALDH1A1MITFHSP90AA1 | |
| SCHEMBL29198714 | 0.94 | LMNA (0.47) | LMNAHPGDALDH1A1MITFHSP90AA1 | |
| SCHEMBL29198713 | 0.85 | LMNA (0.69) | LMNAHPGDALDH1A1MITFHSP90AA1 | |
| SCHEMBL30657001 | 0.85 | LMNA (0.69) | LMNAHPGDALDH1A1MITFHSP90AA1 | |
| SCHEMBL30657004 | 0.80 | LMNA (0.61) | LMNAHPGDALDH1A1MITFHSP90AA1 | |
| SCHEMBL29198710 | 0.80 | LMNA (0.61) | LMNAHPGDALDH1A1MITFHSP90AA1 | |
| SCHEMBL29198719 | 0.80 | LMNA (0.61) | LMNAHPGDALDH1A1MITFHSP90AA1 | |
| SCHEMBL30657007 | 0.77 | MAOB (0.47) | ALDH1A1MAPTHTTSMN1; SMN2KMT2A | |
| SCHEMBL29198711 | 0.76 | ALDH1A1 (0.42) | HPGDALDH1A1MAPTCYP3A4MEN1 | |
| SCHEMBL14970263 | 0.73 | MAPT (0.36) | LMNAHPGDALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069732-B | Preparation method of benzo [ c ] phenanthridine natural product and derivative thereof | 沈阳药科大学 | 2024-04-26 | — | — | CN | disclosed |