Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 5/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 7/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16029255 | 1.00 | TGFBR1 (0.39) | TGFBR1S1PR4MAPTGFERLMNA | |
| SCHEMBL25248350 | 0.85 | TGFBR1 (0.39) | TGFBR1S1PR4MAPTLMNAHPGD | |
| SCHEMBL30086838 | 0.85 | TGFBR1 (0.39) | TGFBR1S1PR4MAPTLMNAHPGD | |
| SCHEMBL16028590 | 0.84 | S1PR4 (0.36) | S1PR4MAPTLMNAHPGDNPC1 | |
| SCHEMBL21426336 | 0.82 | TGFBR1 (0.47) | TGFBR1 | |
| SCHEMBL16028902 | 0.81 | TGFBR1 (0.40) | TGFBR1MAPTLMNAHPGDMEN1 | |
| SCHEMBL16028695 | 0.81 | PIN1 (0.33) | S1PR4MAPTGFERLMNAPIN1 | |
| SCHEMBL21772047 | 0.80 | CSF1R (0.52) | TGFBR1 | |
| SCHEMBL21425579 | 0.80 | TGFBR1 (0.45) | TGFBR1 | |
| SCHEMBL16036508 | 0.80 | TGFBR1 (0.45) | TGFBR1MAPTHPGDNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632907-B1 | N-(AZAARYL)CYCLOLACTAM-1-CARBOXAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | ABBISKO THERAPEUTICS CO LTD (CN) | 2024-02-28 | — | — | EP | disclosed |