Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP1LC3B | Q9GZQ8 | 4/20 | 0.52 |
| ▸ | BRD4 | O60885 | 10/20 | 0.52 |
| ▸ | CRBN | Q96SW2 | 10/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30891812 | 0.96 | MAP1LC3B (0.55) | MAP1LC3BBRD4CRBN | |
| SCHEMBL30891811 | 0.91 | STAT3 (0.53) | MAP1LC3BBRD4CRBN | |
| SCHEMBL30891789 | 0.91 | STAT3 (0.53) | MAP1LC3BBRD4CRBN | |
| SCHEMBL24777871 | 0.90 | CRBN (0.57) | MAP1LC3BBRD4CRBNDDB1 | |
| SCHEMBL26321010 | 0.88 | CRBN (0.64) | MAP1LC3BBRD4CRBNDDB1 | |
| SCHEMBL22075932 | 0.87 | BRD4 (0.57) | MAP1LC3BBRD4CRBNDDB1 | |
| SCHEMBL13621972 | 0.86 | CRBN (0.58) | MAP1LC3BBRD4CRBNDDB1 | |
| SCHEMBL30250216 | 0.86 | CRBN (0.58) | MAP1LC3BBRD4CRBNDDB1 | |
| SCHEMBL25756351 | 0.86 | MAP1LC3B (0.49) | MAP1LC3BBRD4CRBN | |
| SCHEMBL26321021 | 0.86 | CRBN (0.64) | MAP1LC3BBRD4CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777223-A | ARE-PROTAC compound and preparation method and application thereof | 中国药科大学 | 2024-03-29 | — | — | CN | disclosed |