Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | MAP1LC3B | Q9GZQ8 | 7/20 | 0.49 |
| ▸ | BRD4 | O60885 | 6/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 7/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30891789 | 1.00 | STAT3 (0.53) | STAT3MAP1LC3BBRD4CRBN | |
| SCHEMBL25756460 | 0.92 | MAP1LC3B (0.52) | STAT3MAP1LC3BBRD4CRBN | |
| SCHEMBL25031848 | 0.92 | MAP1LC3B (0.52) | STAT3MAP1LC3BBRD4CRBN | |
| SCHEMBL30891812 | 0.92 | MAP1LC3B (0.55) | MAP1LC3BBRD4CRBN | |
| SCHEMBL30891792 | 0.91 | MAP1LC3B (0.52) | MAP1LC3BBRD4CRBN | |
| SCHEMBL25376586 | 0.90 | MAP1LC3B (0.59) | STAT3MAP1LC3BBRD4CRBN | |
| SCHEMBL30550160 | 0.90 | MAP1LC3B (0.59) | STAT3MAP1LC3BBRD4CRBN | |
| SCHEMBL28668320 | 0.89 | STAT3 (0.53) | STAT3MAP1LC3BBRD4CRBN | |
| SCHEMBL23772439 | 0.89 | MAP1LC3B (0.51) | STAT3MAP1LC3BBRD4CRBN | |
| SCHEMBL23772825 | 0.89 | MAP1LC3B (0.51) | STAT3MAP1LC3BBRD4CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777223-A | ARE-PROTAC compound and preparation method and application thereof | 中国药科大学 | 2024-03-29 | — | — | CN | disclosed |