Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.48 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9139429 | 1.00 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2ACYP1A2KDM4E | |
| SCHEMBL13129781 | 0.86 | KMT2A (0.57) | ALDH1A1MEN1KMT2ACYP1A2KDM4E | |
| SCHEMBL7231747 | 0.85 | KDM4E (0.67) | ALDH1A1MEN1KMT2ACYP1A2KDM4E | |
| SCHEMBL5323858 | 0.84 | CYP1A2 (0.51) | ALDH1A1MEN1KMT2ACYP1A2KDM4E | |
| SCHEMBL10830938 | 0.84 | TNF (0.58) | ALDH1A1MEN1KMT2ACYP1A2KDM4E | |
| SCHEMBL10487972 | 0.83 | KDM4E (0.62) | ALDH1A1MEN1KMT2ACYP1A2KDM4E | |
| SCHEMBL13332558 | 0.83 | CYP1A2 (0.62) | ALDH1A1MEN1KMT2ACYP1A2KDM4E | |
| SCHEMBL23997319 | 0.82 | LMNA (0.60) | ALDH1A1MEN1KMT2ACYP1A2KDM4E | |
| SCHEMBL30345078 | 0.82 | LMNA (0.60) | ALDH1A1MEN1KMT2ACYP1A2KDM4E | |
| SCHEMBL3591401 | 0.82 | MEN1 (0.55) | ALDH1A1MEN1KMT2ACYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665729-A1 | DDR1 AND DDR2 INHIBITORS HAVING A DIHYDROBENZIMIDAZOLONE CORE | Redx Pharma Limited (GB) | 2025-12-24 | — | — | EP | disclosed |
| EP-4665728-A1 | DDR1 AND DDR2 INHIBITORS HAVING A DIHYDROBENZIMIDAZOLONE CORE | Redx Pharma Limited (GB) | 2025-12-24 | — | — | EP | disclosed |
| EP-4577543-A1 | PYRIDO-PYRAZOLES AS INHIBITORS OF DDR'S FOR THE TREATMENT OF FIBROTIC DISORDERS AND CANCER | Redx Pharma Limited (GB) | 2025-07-02 | — | — | EP | disclosed |
| CN-119768403-A | Pyridopyrazoles as DDR inhibitors for the treatment of fibrotic disorders and cancer | 莱德克斯制药有限公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024170907-A1 | DDR1 AND DDR2 INHIBITORS HAVING A DIHYDROBENZIMIDAZOLONE CORE | REDX PHARMA LIMITED (GB) | 2024-08-22 | — | — | WO | disclosed |
| WO-2024170909-A1 | DDR1 AND DDR2 INHIBITORS HAVING A DIHYDROBENZIMIDAZOLONE CORE | REDX PHARMA LIMITED (GB) | 2024-08-22 | — | — | WO | disclosed |