Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Taltirelin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRHR known ✓ | P34981 | 4/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Taltirelin SCHEMBL2289290 | 1.00 | TRHR (0.72) | TRHR | |
| Taltirelin SCHEMBL194528 | 0.99 | TRHR (0.73) | TRHR | |
| Taltirelin SCHEMBL13993039 | 0.99 | TRHR (0.73) | TRHR | |
| Taltirelin SCHEMBL2320945 | 0.95 | TRHR (0.69) | TRHR | |
| Azetirelin SCHEMBL195158 | 0.90 | TRHR (0.85) | TRHR | |
| Taltirelin SCHEMBL2321397 | 0.90 | TRHR (0.61) | TRHR | |
| Taltirelin SCHEMBL22077031 | 0.85 | TRHR (0.65) | TRHR | |
| Taltirelin SCHEMBL3188420 | 0.85 | TRHR (0.57) | TRHR | |
| Taltirelin SCHEMBL14280928 | 0.84 | TRHR (0.57) | TRHR | |
| Taltirelin SCHEMBL21219549 | 0.84 | TRHR (0.57) | TRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117899200-A | Medicament for enhancing curative effect of immunotherapy and application of medicament in treating tumors | 华中科技大学 | 2024-04-19 | — | — | CN | claimed |
| CN-117899200-A | Medicament for enhancing curative effect of immunotherapy and application of medicament in treating tumors | 华中科技大学 | 2024-04-19 | — | — | CN | disclosed |