Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29534043 | 0.83 | AAK1 (0.34) | AAK1SSTR4BRD4PAX8BACE1 | |
| SCHEMBL20045662 | 0.83 | AAK1 (0.34) | AAK1SSTR4BRD4PAX8BACE1 | |
| SCHEMBL30936694 | 0.80 | BRD4 (0.36) | AAK1BRD4PAX8BACE1 | |
| SCHEMBL30893241 | 0.79 | MAPT (0.36) | SSTR4BRD4 | |
| SCHEMBL23540776 | 0.77 | AAK1 (0.37) | AAK1SSTR4BRD4PAX8 | |
| SCHEMBL30026361 | 0.77 | AAK1 (0.37) | AAK1SSTR4BRD4PAX8 | |
| SCHEMBL18157852 | 0.74 | BRD4 (0.41) | AAK1BRD4PAX8MT-CO2BACE1 | |
| SCHEMBL23054111 | 0.74 | ALDH1A1 (0.38) | AAK1SSTR4BRD4PAX8 | |
| SCHEMBL25368790 | 0.73 | APP (0.34) | AAK1SSTR4MT-CO2BACE1 | |
| SCHEMBL30936643 | 0.72 | BRD4 (0.37) | AAK1BRD4PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097948-A1 | DEGRADERS OF MDM2 AND USES THEREOF | ROIVANT DISCOVERY, INC. (US) | 2024-05-10 | — | — | WO | disclosed |