Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.31 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20045660 | 0.85 | ALDH1A1 (0.34) | MAPTALDH1A1LMNAATMTDP1 | |
| SCHEMBL30936632 | 0.82 | NPSR1 (0.38) | ALDH1A1LMNATDP1NPSR1HTT | |
| SCHEMBL31220170 | 0.80 | LMNA (0.33) | MAPTALDH1A1LMNATDP1NPSR1 | |
| SCHEMBL25171636 | 0.80 | LMNA (0.33) | MAPTALDH1A1LMNATDP1NPSR1 | |
| SCHEMBL30893303 | 0.80 | NPSR1 (0.38) | MAPTALDH1A1LMNAATMTDP1 | |
| SCHEMBL23540991 | 0.80 | NPSR1 (0.38) | MAPTALDH1A1LMNAATMTDP1 | |
| SCHEMBL30893277 | 0.79 | AAK1 (0.38) | SSTR4BRD4 | |
| SCHEMBL19690540 | 0.78 | ALDH1A1 (0.34) | MAPTALDH1A1LMNAATMTDP1 | |
| SCHEMBL30038538 | 0.78 | ALDH1A1 (0.34) | MAPTALDH1A1LMNAATMTDP1 | |
| SCHEMBL18154006 | 0.77 | ATM (0.43) | MAPTALDH1A1LMNAATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097948-A1 | DEGRADERS OF MDM2 AND USES THEREOF | ROIVANT DISCOVERY, INC. (US) | 2024-05-10 | — | — | WO | disclosed |