Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.53 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 11/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Chloronicotinaldehyde SCHEMBL715765 | 0.94 | — | — | |
| 2-Chloronicotinaldehyde SCHEMBL29828177 | 0.94 | — | — | |
| Formic Acid SCHEMBL28210582 | 0.81 | SMN1; SMN2 (0.48) | TRIM24TRIM33LMNASMN1; SMN2NFE2L2 | |
| SCHEMBL20599365 | 0.79 | TRIM24 (0.48) | TRIM24TRIM33LMNASMN1; SMN2NFE2L2 | |
| SCHEMBL1202413 | 0.78 | ALDH1A1 (0.47) | TRIM24TRIM33LMNASMN1; SMN2NFE2L2 | |
| SCHEMBL1202412 | 0.78 | ALDH1A1 (0.47) | TRIM24TRIM33LMNASMN1; SMN2NFE2L2 | |
| Formic Acid SCHEMBL27951317 | 0.78 | TRIM24 (0.47) | TRIM24TRIM33LMNASMN1; SMN2NFE2L2 | |
| Formic Acid SCHEMBL27896714 | 0.78 | LMNA (0.46) | TRIM24TRIM33LMNASMN1; SMN2KMT2A | |
| SCHEMBL23948729 | 0.76 | TRIM24 (0.50) | TRIM24TRIM33LMNASMN1; SMN2NFE2L2 | |
| Hydrochloric Acid SCHEMBL4048083 | 0.76 | ALDH1A1 (0.46) | TRIM24TRIM33LMNASMN1; SMN2NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117800944-A | Pyridine amide derivative, pharmaceutical composition containing same and medical application of pharmaceutical composition | 苏州阿尔脉生物科技有限公司 | 2024-04-02 | — | — | CN | disclosed |