Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.46 |
| ▸ | CFTR | P13569 | 2/20 | 0.43 |
| ▸ | GOPC | Q9HD26 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16041507 | 0.81 | KDM4E (0.51) | KDM4EKDM4CLRRK2NR1I2SCN1A | |
| SCHEMBL15722447 | 0.81 | HDAC3 (0.54) | KDM4EKDM4CHDAC3HDAC1HDAC2 | |
| SCHEMBL8353923 | 0.81 | HDAC3 (0.54) | KDM4EKDM4CHDAC3HDAC1HDAC2 | |
| SCHEMBL15722551 | 0.81 | HDAC3 (0.54) | KDM4EKDM4CHDAC3HDAC1HDAC2 | |
| SCHEMBL28470886 | 0.81 | KDM4E (0.62) | KDM4EKDM4CCFTRGOPCSLC6A2 | |
| Hydrochloric Acid SCHEMBL11568531 | 0.80 | KDM4E (0.50) | KDM4EKDM4CHDAC3HDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL11228436 | 0.80 | KDM4E (0.50) | KDM4EKDM4CHDAC3HDAC1HDAC2 | |
| SCHEMBL15137193 | 0.79 | KDM4E (0.59) | KDM4EKDM4CSMN1; SMN2GAA | |
| SCHEMBL31285576 | 0.77 | KDM4E (1.00) | KDM4EKDM4CCFTRGOPCSLC6A2 | |
| SCHEMBL8877012 | 0.77 | KDM4E (1.00) | KDM4EKDM4CCFTRGOPCSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240158385-A1 | NOVEL COMPOUNDS | Cerevance, Inc. | 2024-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240158385-A1 | NOVEL COMPOUNDS | KCNK3, KCNA4, KCNK13 | KDM4E 851/4885KDM4C 777/4885HDAC3 345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.