SCHEMBL30894899

SCHEMBL30894899

COc1ccc(C)cc1N=Nc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FTO Q9C0B1 1/20 0.60
▸ MAPT P10636 8/20 0.50
▸ MAPK1 P28482 4/20 0.50
▸ L3MBTL1 Q9Y468 4/20 0.50
▸ NPC1 O15118 2/20 0.50
▸ RAB9A P51151 2/20 0.50
▸ MEN1 O00255 6/20 0.49
▸ KMT2A Q03164 6/20 0.49
▸ TDP1 Q9NUW8 3/20 0.49
▸ SMN1; SMN2 Q16637 2/20 0.49
▸ KDM4E B2RXH2 1/20 0.49
▸ HSP90AA1 P07900 1/20 0.49
▸ HTT P42858 1/20 0.49
▸ MMP14 P50281 1/20 0.49
▸ ACHE P22303 1/20 0.47
▸ PKM P14618 2/20 0.46
▸ ATM Q13315 1/20 0.46
▸ ALDH1A1 P00352 5/20 0.44
▸ POLB P06746 1/20 0.44
▸ APOBEC3A P31941 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30894900 1.00 FTO (0.60) FTOMAPTMAPK1L3MBTL1NPC1
SCHEMBL6451518 0.85 FTO (0.63) FTOMAPTMAPK1L3MBTL1NPC1
SCHEMBL11533075 0.83 MAPT (0.56) FTOMAPTMAPK1L3MBTL1NPC1
SCHEMBL11533079 0.83 MAPT (0.56) FTOMAPTMAPK1L3MBTL1NPC1
SCHEMBL30894901 0.83 CYP19A1 (0.50) MAPTMAPK1L3MBTL1NPC1RAB9A
SCHEMBL28553449 0.81 L3MBTL1 (0.58) FTOMAPTMAPK1L3MBTL1MEN1
SCHEMBL28553450 0.81 L3MBTL1 (0.58) FTOMAPTMAPK1L3MBTL1MEN1
SCHEMBL23559947 0.80 KMT2A (0.60) FTOMAPTMAPK1L3MBTL1NPC1
SCHEMBL1405268 0.80 KMT2A (0.58) FTOMAPTMAPK1L3MBTL1NPC1
SCHEMBL31071661 0.80 KMT2A (0.58) FTOMAPTMAPK1L3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117813394-A Flow cell with dark quencher 因美纳有限公司 2024-04-02 — — CN claimed
CN-117813394-A Flow cell with dark quencher 因美纳有限公司 2024-04-02 — — CN disclosed
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