Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30895272 | 0.80 | PDGFRA (0.38) | CYP19A1CYP2C9CYP11B1CYP11B2KMO | |
| SCHEMBL30895271 | 0.80 | PDGFRA (0.38) | CYP19A1CYP2C9CYP11B1CYP11B2KMO | |
| SCHEMBL15730578 | 0.75 | ESR1 (0.60) | ESR1KMOADORA2AADORA2B | |
| SCHEMBL30895262 | 0.72 | KDM4E (0.31) | — | |
| SCHEMBL15723742 | 0.71 | GRM4 (0.43) | ESR1KDRHTT | |
| SCHEMBL18853871 | 0.71 | ESR1 (0.63) | ESR1KMOSLC22A12ADORA2AADORA2B | |
| SCHEMBL30895264 | 0.71 | IRAK4 (0.40) | — | |
| SCHEMBL176951 | 0.70 | ELANE (0.42) | ESR1KMOSLC22A12HTT | |
| SCHEMBL30895267 | 0.70 | MAPK8 (0.39) | CYP2C9ADORA2AADORA2BHTT | |
| SCHEMBL176840 | 0.67 | ESR2 (0.41) | ESR1KMOSLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4608507-A1 | COMPOUNDS AND COMPOSITIONS AS GPR52 MODULATORS | Neurocrine Biosciences, Inc. (US) | 2025-09-03 | — | — | EP | disclosed |
| WO-2024091538-A1 | COMPOUNDS AND COMPOSITIONS AS GPR52 MODULATORS | NEUROCRINE BIOSCIENCES, INC. (US) | 2024-05-02 | — | — | WO | disclosed |