Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | STK17B | O94768 | 1/20 | 0.38 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22535987 | 0.81 | TDP1 (0.46) | POLBMAPK1ATMLMNAKDM4E | |
| SCHEMBL15933308 | 0.80 | POLB (0.40) | POLBMAPK1ATMLMNAKDM4E | |
| SCHEMBL30895755 | 0.77 | KCNH2 (0.36) | POLBMAPK1ATMLMNAKDM4E | |
| SCHEMBL13977598 | 0.74 | KDM4E (0.49) | POLBMAPK1ATMLMNAKDM4E | |
| SCHEMBL21484075 | 0.74 | POLB (0.59) | POLBMAPK1ATMLMNAGAA | |
| SCHEMBL30662746 | 0.74 | KDM4E (0.40) | POLBMAPK1ATMLMNAKDM4E | |
| SCHEMBL8275252 | 0.74 | KDM4A (0.43) | POLBMAPK1ATMLMNAKDM4E | |
| SCHEMBL22535990 | 0.73 | TDP1 (0.44) | POLBMAPK1ATMLMNAKDM4E | |
| SCHEMBL16628028 | 0.72 | KDM4E (0.44) | POLBMAPK1ATMLMNAKDM4E | |
| SCHEMBL22535973 | 0.71 | TDP1 (0.43) | LMNAKDM4ETDP1GAAKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024090469-A1 | FUSED PYRIDAZINE DERIVATIVE | アステラス製薬株式会社 | 2024-05-02 | — | — | WO | disclosed |