Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | TNKS | O95271 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | INMT | O95050 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | BRD2 | P25440 | 1/20 | 0.31 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12428932 | 0.84 | HSD17B10 (0.46) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL24405342 | 0.81 | HSD17B10 (0.50) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL20563009 | 0.79 | ALDH1A1 (0.44) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL14283936 | 0.76 | ALDH1A1 (0.44) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL22476657 | 0.73 | ALDH1A1 (0.42) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL15628980 | 0.72 | ALDH1A1 (0.50) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL520908 | 0.71 | BRD4 (0.51) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL30464716 | 0.71 | ALDH1A1 (0.58) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL31716065 | 0.71 | ALDH1A1 (0.58) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL1453685 | 0.71 | ALDH1A1 (0.58) | ALDH1A1GAAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612128-A1 | COMPOUNDS AND THEIR USE FOR TREATMENT OF HEMOGLOBINOPATHIES | Bristol-Myers Squibb Company (US) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024097932-A1 | COMPOUNDS AND THEIR USE FOR TREATMENT OF HEMOGLOBINOPATHIES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-05-10 | — | — | WO | disclosed |