Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 9/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | EDNRB | P24530 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25282000 | 1.00 | BRD4 (0.42) | BRD4CYP1A2CHRNB2CHRNA4ERN1 | |
| SCHEMBL6589213 | 0.81 | BRD4 (0.44) | BRD4CHRNB2CHRNA4ERN1ALDH1A1 | |
| SCHEMBL30690121 | 0.81 | TSHR (0.44) | BRD4CYP1A2ALDH1A1MAPT | |
| SCHEMBL28912013 | 0.81 | CA12 (0.46) | BRD4ALDH1A1MAPT | |
| SCHEMBL30690118 | 0.79 | BRD4 (0.45) | BRD4CYP1A2ALDH1A1MAPT | |
| SCHEMBL28551101 | 0.78 | BRD4 (0.44) | BRD4CHRNB2CHRNA4ERN1ALDH1A1 | |
| SCHEMBL722050 | 0.74 | BRD4 (0.46) | BRD4CHRNB2CHRNA4 | |
| SCHEMBL30896376 | 0.74 | DYRK1A (0.38) | BRD4ERN1ALDH1A1MAPT | |
| SCHEMBL28550968 | 0.73 | BRD4 (0.38) | BRD4MAPT | |
| SCHEMBL17307557 | 0.71 | BRD4 (0.41) | BRD4CHRNB2CHRNA4ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612128-A1 | COMPOUNDS AND THEIR USE FOR TREATMENT OF HEMOGLOBINOPATHIES | Bristol-Myers Squibb Company (US) | 2025-09-10 | — | — | EP | disclosed |
| CN-120129677-A | Compounds and their use for the treatment of heme lesions | 百时美施贵宝公司 | 2025-06-10 | — | — | CN | disclosed |
| CN-118401502-A | Benzothiazole, benzisoxazole and benzodioxole analogs as RXFP1 receptor agonists | 百时美施贵宝公司 | 2024-07-26 | — | — | CN | disclosed |
| WO-2024097932-A1 | COMPOUNDS AND THEIR USE FOR TREATMENT OF HEMOGLOBINOPATHIES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-05-10 | — | — | WO | disclosed |