Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 14/20 | 0.38 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28555904 | 0.82 | HSPB1 (0.32) | HSPB1MAPTHTTGAATDP1 | |
| SCHEMBL6589213 | 0.78 | BRD4 (0.44) | BRD4MAPTHTTTDP1MEN1 | |
| SCHEMBL28541638 | 0.78 | HPGD (0.43) | HSPB1MAPTGAATDP1L3MBTL1 | |
| SCHEMBL28544922 | 0.76 | S1PR4 (0.47) | BRD4MAPTTDP1LMNA | |
| SCHEMBL28551101 | 0.76 | BRD4 (0.44) | BRD4MAPTHTTTDP1MEN1 | |
| SCHEMBL25282000 | 0.73 | BRD4 (0.42) | BRD4MAPT | |
| SCHEMBL30690121 | 0.73 | TSHR (0.44) | BRD4MAPTTDP1L3MBTL1MEN1 | |
| SCHEMBL28912013 | 0.73 | CA12 (0.46) | BRD4MAPTLMNA | |
| SCHEMBL30896402 | 0.73 | BRD4 (0.42) | BRD4MAPT | |
| SCHEMBL28551909 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109574945-B | Isoxazoline derivatives and their use in agriculture | 东莞市东阳光农药研发有限公司 | 2021-04-20 | — | — | CN | disclosed |