Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2028838 | 0.94 | CHRM2 (0.36) | CHRM2CHRM1ALDH1A1KDM4EKMT2A | |
| SCHEMBL5062396 | 0.81 | CHRM2 (0.40) | CHRM2CHRM1ALDH1A1KDM4EKMT2A | |
| SCHEMBL4606042 | 0.79 | CHRM2 (0.45) | CHRM2CHRM1ALDH1A1KDM4EKMT2A | |
| SCHEMBL3911963 | 0.79 | CHRM2 (0.39) | CHRM2CHRM1ALDH1A1KDM4EKMT2A | |
| SCHEMBL6370319 | 0.79 | KMT2A (0.42) | CHRM2CHRM1ALDH1A1KDM4EKMT2A | |
| SCHEMBL20495576 | 0.77 | KMT2A (0.47) | CHRM2CHRM1ALDH1A1KDM4EKMT2A | |
| SCHEMBL72732 | 0.77 | KMT2A (0.47) | CHRM2CHRM1ALDH1A1KDM4EKMT2A | |
| Water SCHEMBL20475938 | 0.76 | KMT2A (0.46) | CHRM2CHRM1ALDH1A1KDM4EKMT2A | |
| Water SCHEMBL72731 | 0.76 | KMT2A (0.46) | CHRM2CHRM1ALDH1A1KDM4EKMT2A | |
| Water SCHEMBL6936586 | 0.76 | KMT2A (0.46) | CHRM2CHRM1ALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6979442-B1 | Stabilized protein compositions | PFIZER INC. (US) | 2005-12-27 | — | — | US | claimed |
| EP-3265558-B1 | STABILIZED RNA SOLUTIONS | BIO RAD LABORATORIES (US) | 2020-05-06 | — | — | EP | disclosed |
| US-9896682-B2 | Stabilized RNA solutions | BIO-RAD LABORATORIES, INC. (US) | 2018-02-20 | — | — | US | disclosed |
| EP-3265558-A1 | STABILIZED RNA SOLUTIONS | Bio-Rad Laboratories, Inc. (US) | 2018-01-10 | — | — | EP | disclosed |
| WO-2016144891-A1 | STABILIZED RNA SOLUTIONS | BIO-RAD LABORATORIES, INC. (US) | 2016-09-15 | — | — | WO | disclosed |
| US-20160257950-A1 | STABILIZED RNA SOLUTIONS | BIO-RAD LABORATORIES, INC. | 2016-09-08 | — | — | US | disclosed |
| US-20140141089-A1 | Nanoparticles, Compositions Thereof, and Methods of Use, and Methods of Making the Same | COLORADO SCHOOL OF MINES (US) | 2014-05-22 | — | — | US | disclosed |
| US-8496935-B2 | Immunosuppressive polypeptides and nucleic acids | PERSEID THERAPEUTICS LLC (US) | 2013-07-30 | — | — | US | disclosed |
| US-8491899-B2 | Immunosuppressive polypeptides and nucleic acids | PERSEID THERAPEUTICS LLC (US) | 2013-07-23 | — | — | US | disclosed |
| EP-2612868-A1 | Immunosuppressive polypeptides and nucleic acids | Perseid Therapeutics LLC (US) | 2013-07-10 | — | — | EP | disclosed |
| US-6248353-B1 | INCUBATION MEMBRANE PROTEIN WITH LIPOSOME | DADE BEHRING INC. | 2001-06-19 | — | — | US | disclosed |
| WO-2001041740-A2 | RECONSTITUTION OF PURIFIED MEMBRANE PROTEINS INTO PREFORMED LIPOSOMES | DADE BEHRING INC. (US) | 2001-06-14 | — | — | WO | disclosed |
| US-6165981-A | Stabilizing solutions for proteins and peptides | DADE BEHRING INC. (US) | 2000-12-26 | — | — | US | disclosed |
| EP-0988861-A1 | Stabilized protein compositions | Pfizer Products Inc. (US) | 2000-03-29 | — | — | EP | disclosed |
| EP-0759074-B1 | STABILIZING SOLUTIONS FOR TROPONIN | DADE BEHRING INC (US) | 1998-07-08 | — | — | EP | disclosed |
| EP-0565665-B1 | PREPARATION OF PROTHROMBIN TIME REAGENTS FROM RECOMBINANT HUMAN TISSUE FACTOR AND SYNTHETIC PHOSPHOLIPIDS | DADE INT INC (US) | 1998-03-04 | — | — | EP | disclosed |
| US-5625036-A | Preparation of prothrombin time reagents from recombinant human tissue factor and purified natural and synthetic phospholipids | DADE INTERNATIONAL INC. (US) | 1997-04-29 | — | — | US | disclosed |
| EP-0759074-A1 | STABILIZING SOLUTIONS FOR PROTEINS AND PEPTIDES | DADE INTERNATIONAL INC. (US) | 1997-02-26 | — | — | EP | disclosed |
| WO-1996027661-A1 | STABILIZING SOLUTIONS FOR PROTEINS AND PEPTIDES | DADE INTERNATIONAL INC. (US) | 1996-09-12 | — | — | WO | disclosed |
| WO-1993007492-A1 | PREPARATION OF PROTHROMBIN TIME REAGENTS FROM RECOMBINANT HUMAN TISSUE FACTOR AND PURIFIED NATURAL AND SYNTHETIC PHOSPHOLIPIDS | BAXTER DIAGNOSTICS INC. (US) | 1993-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140141089-A1 | Nanoparticles, Compositions Thereof, and Methods of Use, and Methods of Making the Same | NPC1L1, LIPA, NPC1 | CHRM2 4687/4885CHRM1 4813/4885ALDH1A1 2039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.