SCHEMBL6370319

SCHEMBL6370319

NC(CN1CCN(CCO)CC1)CS(=O)(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.42
HTT P42858 2/20 0.42
LMNA P02545 1/20 0.42
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
ALDH1A1 P00352 4/20 0.36
KDM4E B2RXH2 1/20 0.36
CHRM2 P08172 1/20 0.33
CHRM1 P11229 1/20 0.33
MAPT P10636 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TERT O14746 1/20 0.31
HSD11B1 P28845 1/20 0.31
MEN1 O00255 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9493028 0.81 ALDH1A1 (0.33) KMT2AHTTLMNACA12CA1
SCHEMBL20495576 0.81 KMT2A (0.47) KMT2AHTTLMNAALDH1A1KDM4E
SCHEMBL72732 0.81 KMT2A (0.47) KMT2AHTTLMNAALDH1A1KDM4E
Water SCHEMBL1444204 0.79 KMT2A (0.46) KMT2AHTTLMNAALDH1A1KDM4E
SCHEMBL3089652 0.79 CHRM2 (0.39) KMT2AHTTLMNACA12CA1
Water SCHEMBL20475938 0.79 KMT2A (0.46) KMT2AHTTLMNAALDH1A1KDM4E
Water SCHEMBL72731 0.79 KMT2A (0.46) KMT2AHTTLMNAALDH1A1KDM4E
Water SCHEMBL6936586 0.79 KMT2A (0.46) KMT2AHTTLMNAALDH1A1KDM4E
Water SCHEMBL15641759 0.77 KMT2A (0.44) KMT2AHTTLMNAALDH1A1KDM4E
SCHEMBL4259360 0.77 HTT (0.50) KMT2AHTTLMNACA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6979442-B1 Stabilized protein compositions PFIZER INC. (US) 2005-12-27 US claimed
EP-3265558-B1 STABILIZED RNA SOLUTIONS BIO RAD LABORATORIES (US) 2020-05-06 EP disclosed
US-9896682-B2 Stabilized RNA solutions BIO-RAD LABORATORIES, INC. (US) 2018-02-20 US disclosed
EP-3265558-A1 STABILIZED RNA SOLUTIONS Bio-Rad Laboratories, Inc. (US) 2018-01-10 EP disclosed
WO-2016144891-A1 STABILIZED RNA SOLUTIONS BIO-RAD LABORATORIES, INC. (US) 2016-09-15 WO disclosed
US-20160257950-A1 STABILIZED RNA SOLUTIONS BIO-RAD LABORATORIES, INC. 2016-09-08 US disclosed
EP-0988861-A1 Stabilized protein compositions Pfizer Products Inc. (US) 2000-03-29 EP disclosed