Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | ADCY5 | O95622 | 11/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | PI4KA | P42356 | 2/20 | 0.35 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.35 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30897072 | 1.00 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4DADCY5 | |
| SCHEMBL6427905 | 0.83 | ADORA2A (0.56) | ADCY5ADORA2AADORA3ADORA1PI4KA | |
| SCHEMBL21682109 | 0.77 | PRMT5 (0.39) | FGFR1FGFR4 | |
| SCHEMBL21682107 | 0.77 | PRMT5 (0.39) | FGFR1FGFR4 | |
| SCHEMBL30897109 | 0.73 | ADCY5 (0.45) | PDE4APDE4BPDE4CPDE4DADCY5 | |
| SCHEMBL8885246 | 0.73 | ADCY5 (0.45) | PDE4APDE4BPDE4CPDE4DADCY5 | |
| SCHEMBL4352091 | 0.73 | ADCY5 (0.45) | PDE4APDE4BPDE4CPDE4DADCY5 | |
| SCHEMBL24196376 | 0.72 | ADORA2A (0.65) | PDE4APDE4BPDE4CPDE4DADCY5 | |
| SCHEMBL26804584 | 0.71 | AHCY (0.42) | PDE4APDE4BPDE4CPDE4DFDPS | |
| SCHEMBL7592748 | 0.70 | ADCY5 (0.54) | PDE4DADCY5ADORA2AADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024107859-A1 | CYCLOPENTENE-OXYMETHYLENE PHOSPHONAMIDATES AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | ROME THERAPEUTICS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |