Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.56 |
| ▸ | PI4KA | P42356 | 3/20 | 0.54 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.54 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.54 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.54 |
| ▸ | ADCY5 | O95622 | 11/20 | 0.53 |
| ▸ | AHCY | P23526 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30897077 | 0.83 | PDE4A (0.39) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL30897072 | 0.83 | PDE4A (0.39) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL6427683 | 0.75 | ADORA3 (0.48) | ADORA3BLM | |
| SCHEMBL12280365 | 0.74 | ADORA2A (0.63) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL30166469 | 0.74 | ADORA2A (0.63) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL1934441 | 0.74 | ADORA2A (0.63) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL8660508 | 0.73 | ADCY5 (0.64) | ADORA2AADCY5AHCY | |
| SCHEMBL9147328 | 0.73 | ADCY5 (0.64) | ADORA2AADCY5AHCY | |
| SCHEMBL28984637 | 0.72 | ADORA2A (1.00) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL8885831 | 0.72 | ADORA2A (0.60) | ADORA2API4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1050525-B1 | SUBSTANCES CAPABLE OF INDUCING APOPTOSIS | TAKARA BIO INC (JP) | 2005-08-31 | — | — | EP | claimed |
| US-6809091-B1 | RHEUMATISM; 2-(3,4-DIHYDROXY-1-BUTENYL)-4-(2-FORMYLVINYL)-1,3-DIOXOLANE; 4-(9-GUANINYL)-2-CYCLOPENTEN-1-ONE | TAKARA BIO INC. (JP) | 2004-10-26 | — | — | US | claimed |
| EP-1050525-A1 | SUBSTANCES CAPABLE OF INDUCING APOPTOSIS | Takara Shuzo Co, Ltd. (JP) | 2000-11-08 | — | — | EP | claimed |
| EP-1050525-B1 | SUBSTANCES CAPABLE OF INDUCING APOPTOSIS | TAKARA BIO INC (JP) | 2005-08-31 | — | — | EP | disclosed |
| US-6809091-B1 | RHEUMATISM; 2-(3,4-DIHYDROXY-1-BUTENYL)-4-(2-FORMYLVINYL)-1,3-DIOXOLANE; 4-(9-GUANINYL)-2-CYCLOPENTEN-1-ONE | TAKARA BIO INC. (JP) | 2004-10-26 | — | — | US | disclosed |
| EP-1170007-A1 | REMEDIES | Takara Shuzo Co, Ltd. (JP) | 2002-01-09 | — | — | EP | disclosed |
| EP-1050525-A1 | SUBSTANCES CAPABLE OF INDUCING APOPTOSIS | Takara Shuzo Co, Ltd. (JP) | 2000-11-08 | — | — | EP | disclosed |