SCHEMBL30897173

SCHEMBL30897173

COc1ncc(C=O)c(N2CCC(NC(=O)OC(C)(C)C)CC2)c1Br

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CKS1B P61024 1/20 0.46
▸ SKP1 P63208 1/20 0.46
▸ SKP2 Q13309 1/20 0.46
▸ SUV39H2 Q9H5I1 5/20 0.40
▸ PIM1 P11309 1/20 0.39
▸ PIM3 Q86V86 1/20 0.39
▸ PIM2 Q9P1W9 1/20 0.39
▸ PDE10A Q9Y233 1/20 0.38
▸ CTSK P43235 2/20 0.38
▸ RET P07949 1/20 0.38
▸ CFTR P13569 1/20 0.38
▸ JAK3 P52333 1/20 0.37
▸ BTK Q06187 1/20 0.37
▸ DRD2 P14416 1/20 0.37
▸ MAP4K4 O95819 2/20 0.37
▸ OPRM1 P35372 1/20 0.37
▸ OPRD1 P41143 1/20 0.37
▸ OPRK1 P41145 1/20 0.37
▸ OGFRL1 Q5TC84 1/20 0.37
▸ KCNA3 P22001 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23658236 0.85 CKS1B (0.46) CKS1BSKP1SKP2SUV39H2PIM1
SCHEMBL30079658 0.83 CKS1B (0.47) CKS1BSKP1SKP2SUV39H2PIM1
SCHEMBL28777527 0.81 JAK3 (0.49) CKS1BSKP1SKP2SUV39H2PIM1
SCHEMBL29653516 0.81 JAK3 (0.49) CKS1BSKP1SKP2SUV39H2PIM1
SCHEMBL28777529 0.81 JAK3 (0.49) CKS1BSKP1SKP2SUV39H2PIM1
SCHEMBL22976541 0.80 CKS1B (0.45) CKS1BSKP1SKP2SUV39H2PIM1
SCHEMBL31243162 0.80 SUV39H2 (0.44) CKS1BSKP1SKP2SUV39H2PIM1
SCHEMBL22976538 0.80 CKS1B (0.45) CKS1BSKP1SKP2SUV39H2PIM1
SCHEMBL29653512 0.80 SUV39H2 (0.44) CKS1BSKP1SKP2SUV39H2PIM1
SCHEMBL30897138 0.78 CKS1B (0.48) CKS1BSKP1SKP2SUV39H2PIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4608808-A1 SOMATOSTATIN RECEPTOR 2 AGONISTS AND USES THEREOF Basecamp Bio Inc. (KY) 2025-09-03 — — EP disclosed
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