Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.46 |
| ▸ | SKP1 | P63208 | 1/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.46 |
| ▸ | SUV39H2 | Q9H5I1 | 5/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20500351 | 0.88 | CKS1B (0.47) | CKS1BSKP1SKP2SUV39H2PDE10A | |
| SCHEMBL21810299 | 0.87 | CKS1B (0.46) | CKS1BSKP1SKP2SUV39H2PDE10A | |
| SCHEMBL20500375 | 0.87 | CKS1B (0.46) | CKS1BSKP1SKP2SUV39H2PDE10A | |
| SCHEMBL30254917 | 0.87 | OPRK1 (0.36) | CKS1BSKP1SKP2OPRK1 | |
| SCHEMBL21810232 | 0.85 | CKS1B (0.45) | CKS1BSKP1SKP2SUV39H2PDE10A | |
| SCHEMBL20500497 | 0.85 | CKS1B (0.45) | CKS1BSKP1SKP2SUV39H2PDE10A | |
| SCHEMBL30897173 | 0.85 | CKS1B (0.46) | CKS1BSKP1SKP2SUV39H2PDE10A | |
| SCHEMBL20500374 | 0.83 | CKS1B (0.43) | CKS1BSKP1SKP2SUV39H2PDE10A | |
| SCHEMBL20500436 | 0.81 | CKS1B (0.48) | CKS1BSKP1SKP2SUV39H2PDE10A | |
| SCHEMBL20500433 | 0.81 | SSTR2 (0.42) | CKS1BSKP1SKP2SUV39H2CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110650951-B | Somatostatin modulators and uses thereof | 克林提克斯医药股份有限公司 | 2023-02-24 | — | — | CN | disclosed |
| US-11072598-B2 | Somatostatin modulators and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2021-07-27 | — | — | US | disclosed |
| CN-110650951-A | Somatostatin modulators and uses thereof | 克林提克斯医药股份有限公司 | 2020-01-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11072598-B2 | Somatostatin modulators and uses thereof | SSTR5, SSTR2, SSTR4 | CKS1B 3617/4885SKP1 4341/4885SKP2 4134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.