Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3599686 | 0.82 | LMNA (0.68) | LMNAMAPTALDH1A1CASP1CASP7 | |
| SCHEMBL6873842 | 0.80 | LMNA (0.65) | LMNAMAPTALDH1A1CASP1CASP7 | |
| SCHEMBL30897395 | 0.80 | LMNA (0.65) | LMNAMAPTALDH1A1CASP1CASP7 | |
| SCHEMBL10099692 | 0.80 | MAPT (0.72) | LMNAMAPTALDH1A1CASP1CASP7 | |
| Hydrochloric Acid SCHEMBL8011144 | 0.79 | LMNA (0.71) | LMNAMAPTALDH1A1CASP1CASP7 | |
| SCHEMBL6873837 | 0.79 | LMNA (0.64) | LMNAMAPTALDH1A1CASP1CASP7 | |
| SCHEMBL21855769 | 0.79 | HSD17B10 (0.68) | LMNAMAPTALDH1A1CASP1CASP7 | |
| SCHEMBL29056650 | 0.78 | NPY1R (0.56) | LMNAMAPTALDH1A1L3MBTL1TSHR | |
| SCHEMBL6529824 | 0.78 | LMNA (0.62) | LMNAMAPTALDH1A1CASP1CASP7 | |
| SCHEMBL29056692 | 0.78 | HRH1 (0.45) | LMNAL3MBTL1TSHRPOLBUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4605398-A1 | BICYCLIC FERROPORTIN INHIBITORS | Vifor (International) AG (CH) | 2025-08-27 | — | — | EP | disclosed |
| WO-2024083980-A1 | BICYCLIC FERROPORTIN INHIBITORS | VIFOR (INTERNATIONAL) AG (CH) | 2024-04-25 | — | — | WO | disclosed |