Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 6/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | BUB1 | O43683 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18424882 | 0.87 | PTPN2 (0.45) | PTPN2PTPN1PTPN6ABL1RIN1 | |
| SCHEMBL16812432 | 0.87 | PTPN2 (0.45) | PTPN2PTPN1PTPN6ABL1RIN1 | |
| SCHEMBL22788738 | 0.77 | PTPN2 (0.58) | PTPN2PTPN1PTPN6ABL1RIN1 | |
| SCHEMBL30785575 | 0.77 | GAA (0.55) | PTPN1NPC1RAB9ANAMPTHDAC1 | |
| SCHEMBL25307728 | 0.77 | GPR119 (0.46) | GPR119CYP2C9 | |
| SCHEMBL21640789 | 0.76 | DEGS1 (0.54) | PTPN2PTPN1PTPN6ABL1RIN1 | |
| SCHEMBL30585711 | 0.76 | DEGS1 (0.54) | PTPN2PTPN1PTPN6ABL1RIN1 | |
| SCHEMBL4911832 | 0.75 | LMNA (0.51) | PTPN2PTPN1PTPN6ABL1RIN1 | |
| SCHEMBL15649415 | 0.75 | PARP1 (0.49) | PTPN2PTPN1PTPN6ABL1RIN1 | |
| SCHEMBL5492751 | 0.74 | NTRK1 (0.44) | PTPN2PTPN1PTPN6ABL1RIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4605398-A1 | BICYCLIC FERROPORTIN INHIBITORS | Vifor (International) AG (CH) | 2025-08-27 | — | — | EP | disclosed |
| WO-2024083980-A1 | BICYCLIC FERROPORTIN INHIBITORS | VIFOR (INTERNATIONAL) AG (CH) | 2024-04-25 | — | — | WO | disclosed |