Methacrylic Acid

Methacrylic Acid

SCHEMBL3089828

C=C(C)C(=O)O.C=C(C)C(=O)OCC(C)C.C=CC(=O)OCC(C)C

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 11/20 0.68
HPGD P15428 2/20 0.36
ALDH1A1 P00352 8/20 0.35
TP53 P04637 3/20 0.35
HIF1A Q16665 3/20 0.35
CYP3A4 P08684 2/20 0.35
HSD17B10 Q99714 1/20 0.35
THRB P10828 3/20 0.35
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6014066 0.95 TSHR (0.75) TSHRHPGDALDH1A1TP53HIF1A
Acrylic Acid SCHEMBL3180168 0.94 TSHR (0.68) TSHRHPGDALDH1A1TP53HIF1A
Methacrylic Acid SCHEMBL3100294 0.93 TSHR (0.78) TSHRHPGDALDH1A1TP53HIF1A
Methacrylic Acid SCHEMBL7057335 0.92 TSHR (0.75) TSHRHPGDALDH1A1TP53HIF1A
Methacrylic Acid SCHEMBL28071865 0.89 TSHR (0.54) TSHRHPGDTHRBSMN1; SMN2
Methacrylic Acid SCHEMBL1472434 0.88 TSHR (0.88) TSHRHPGDALDH1A1THRBSMN1; SMN2
Methacrylic Acid SCHEMBL27888179 0.87 TSHR (0.49) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27504091 0.87 TSHR (0.72) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL11825846 0.87 TSHR (0.72) TSHRHPGDALDH1A1TP53HIF1A
Acrylic Acid SCHEMBL1473118 0.86 TSHR (0.78) TSHRHPGDALDH1A1CYP3A4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11229594-B2 Oil-in-water emulsion composition L'OREAL (FR) 2022-01-25 US disclosed
EP-3341083-A1 OIL-IN-WATER EMULSION COMPOSITION L'Oréal (FR) 2018-07-04 EP disclosed
US-20180168992-A1 OIL-IN-WATER EMULSION COMPOSITION L'OREAL (FR) 2018-06-21 US disclosed
WO-2017030106-A1 OIL-IN-WATER EMULSION COMPOSITION L'OREAL (FR) 2017-02-23 WO disclosed
US-7803877-B2 Block polymers and cosmetic compositions and processes comprising them L'OREAL S.A. (FR) 2010-09-28 US disclosed
US-20080050329-A1 Composition for Coating Keratin Fibres Comprising a Block Polymer and Fibres L'OREAL S.A. (FR) 2008-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11229594-B2 Oil-in-water emulsion composition SQLE, EPCAM, OR10J3 TSHR 3297/4885HPGD 64/4885ALDH1A1 2203/4885
US-20180168992-A1 OIL-IN-WATER EMULSION COMPOSITION SQLE, EPCAM, OR10J3 TSHR 3297/4885HPGD 64/4885ALDH1A1 2203/4885
US-20080050329-A1 Composition for Coating Keratin Fibres Comprising a Block Polymer and Fibres KRT18, KIF5B, MARK3 TSHR 4027/4885HPGD 2305/4885ALDH1A1 4059/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.