Sugi Predict

Sugi Predict / Compounds / Methacrylic Acid

Methacrylic Acid

Methacrylic Acid

SCHEMBL3100294

C=C(C)C(=O)O.C=CC(=O)OCC(C)C

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 9/20 0.78
▸ HPGD P15428 2/20 0.40
▸ ALDH1A1 P00352 8/20 0.39
▸ TP53 P04637 3/20 0.39
▸ HIF1A Q16665 3/20 0.39
▸ CYP3A4 P08684 2/20 0.39
▸ HSD17B10 Q99714 1/20 0.39
▸ SMN1; SMN2 Q16637 2/20 0.36
▸ MAPK1 P28482 1/20 0.36
▸ THRB P10828 2/20 0.34
▸ RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL7057335 0.98 TSHR (0.75) TSHRHPGDALDH1A1TP53HIF1A
Methacrylic Acid SCHEMBL3089828 0.93 TSHR (0.68) TSHRHPGDALDH1A1TP53HIF1A
Methacrylic Acid SCHEMBL27411059 0.89 TSHR (0.60) TSHRHPGDALDH1A1TP53HIF1A
Methacrylic Acid SCHEMBL1473452 0.89 TSHR (0.60) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL16448 0.88 — —
SCHEMBL28192845 0.88 TSHR (1.00) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL6014066 0.87 TSHR (0.75) TSHRHPGDALDH1A1TP53HIF1A
Methacrylic Acid SCHEMBL27841019 0.87 TSHR (0.58) TSHRHPGDALDH1A1TP53HIF1A
Acrylic Acid SCHEMBL8390074 0.86 TSHR (0.88) TSHRHPGDALDH1A1TP53HIF1A
Acrylic Acid SCHEMBL3180168 0.86 TSHR (0.68) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1864989-A Layered structure, method of its preparation and use CELANESE EMULSIONS GMBH (DE) 2006-11-22 — — CN claimed
US-20060257673-A1 Laminates, their production and use CELANESE EMULSIONS GMBH (DE) 2006-11-16 — — US claimed
EP-1675558-A1 COSMETIC COMPOSITION COMPRISING A TENSIONING AGENT AND A PARTICULAR BLOCK ETHYLENIC POLYMER L'OREAL (FR) 2006-07-05 — — EP claimed
US-20050124759-A1 Aqueous coating compositions method for the production thereof and their use for producing in particular thixotropic coating compositions CELANESE EMULSIONS GMBH (DE) 2005-06-09 — — US claimed
WO-2005030158-A1 COSMETIC COMPOSITION COMPRISING A TENSIONING AGENT AND A PARTICULAR BLOCK ETHYLENIC POLYMER L'OREAL (FR) 2005-04-07 — — WO claimed
EP-4185652-A1 ADHESIVE COMPOSITION FOR MAKING WATERPROOF BREATHABLE ARTICLES Bostik SA (FR) 2023-05-31 — — EP disclosed
CN-112759864-B PVC/ABS alloy material and preparation method and application thereof 金发科技股份有限公司 2022-05-17 — — CN disclosed
CN-107743392-B Oil-in-water emulsion composition 莱雅公司 2021-05-07 — — CN disclosed
CN-110305242-A Preparation method of styrene-acrylic colloid emulsion with high solid content 南京工业大学 2019-10-08 — — CN disclosed
CN-108307633-A Acid Destabilization of Elastomeric Roof Coatings 罗门哈斯公司 2018-07-20 — — CN disclosed
US-20150305991-A1 PROCESS FOR MAKING UP KERATIN FIBRES AND PACKAGING ASSEMBLY L`OREAL (FR) 2015-10-29 — — US disclosed
US-8436088-B2 Plasters and renders and paints, copolymer dispersions and their use CELANESE EMULSIONS GMBH (DE) 2013-05-07 — — US disclosed
US-20100254929-A1 METHOD FOR MAKING UP THE EYELASHES COMPRISING THE APPLICATION OF 2 COMPOSITIONS L'OREAL (FR) 2010-10-07 — — US disclosed
US-20100144925-A1 Plasters and Renders and Paints, Copolymer Dispersions and Their Use NUTRINOVA NUTRITION SPECIALTIES & FOOD INGREDIENTS GMBH (DE) 2010-06-10 — — US disclosed
US-20100021406-A1 PROCESS FOR MAKING UP KERATIN FIBRES AND PACKAGING ASSEMBLY L'OREAL S.A. (FR) 2010-01-28 — — US disclosed
US-20080014235-A1 Novel Block Polymers and Cosmetic Compositions and Processes Comprising Them L'OREAL 2008-01-17 — — US disclosed
CN-1864989-A Layered structure, method of its preparation and use CELANESE EMULSIONS GMBH (DE) 2006-11-22 — — CN disclosed
US-20060257673-A1 Laminates, their production and use CELANESE EMULSIONS GMBH (DE) 2006-11-16 — — US disclosed
US-20050124759-A1 Aqueous coating compositions method for the production thereof and their use for producing in particular thixotropic coating compositions CELANESE EMULSIONS GMBH (DE) 2005-06-09 — — US disclosed
US-5030394-A PVdF-based powder coatings LABOFINA, S.A. (BE) 1991-07-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080014235-A1 Novel Block Polymers and Cosmetic Compositions and Processes Comprising Them FANCI, GDI2, TBCB TSHR 2647/4885HPGD 2470/4885ALDH1A1 1656/4885
US-20150305991-A1 PROCESS FOR MAKING UP KERATIN FIBRES AND PACKAGING ASSEMBLY KRT18, CUTA, COL1A1 TSHR 4521/4885HPGD 1473/4885ALDH1A1 3012/4885
US-20100021406-A1 PROCESS FOR MAKING UP KERATIN FIBRES AND PACKAGING ASSEMBLY KRT18, CUTA, COL1A1 TSHR 4521/4885HPGD 1473/4885ALDH1A1 3012/4885
US-20100254929-A1 METHOD FOR MAKING UP THE EYELASHES COMPRISING THE APPLICATION OF 2 COMPOSITIONS KRT18, DSG1, DDX3X TSHR 4063/4885HPGD 2686/4885ALDH1A1 2145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.