SCHEMBL30898293

SCHEMBL30898293

O=c1[nH]c2ccccc2n(Cc2ccc3ccccc3c2)c1=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.50
LMNA P02545 1/20 0.49
HTT P42858 1/20 0.49
GRIA1 P42261 2/20 0.47
GRIA2 P42262 2/20 0.47
GRIA3 P42263 2/20 0.47
GRIA4 P48058 2/20 0.47
VDR P11473 1/20 0.47
CFTR P13569 1/20 0.44
GAA P10253 1/20 0.44
HTR3A P46098 1/20 0.43
APOBEC3G Q9HC16 1/20 0.42
KDM4E B2RXH2 1/20 0.42
PARP1 P09874 2/20 0.42
ALDH1A1 P00352 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HIF1A Q16665 1/20 0.42
HDAC1 Q13547 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29212231 1.00 DAO (0.50) DAOLMNAHTTGRIA1GRIA2
SCHEMBL30530478 0.82 APOBEC3G (0.61) LMNAHTTGRIA1GRIA2GRIA3
SCHEMBL7329647 0.82 APOBEC3G (0.61) LMNAHTTGRIA1GRIA2GRIA3
SCHEMBL7321461 0.80 KDM4E (0.67) LMNAHTTGRIA1GRIA2GRIA3
Acetic Acid SCHEMBL11489515 0.79 LMNA (0.58) DAOLMNAHTTVDRAPOBEC3G
SCHEMBL28403947 0.73 KMT2A (0.68) DAOVDRCFTRGAAHTR3A
SCHEMBL29579885 0.72 CYP1A2 (0.69) HTTGRIA1GRIA2GRIA3GRIA4
SCHEMBL982104 0.72 CYP1A2 (0.69) HTTGRIA1GRIA2GRIA3GRIA4
SCHEMBL9395535 0.72 GRIA1 (0.47) LMNAHTTGRIA1GRIA2GRIA3
SCHEMBL30898291 0.72 GRIA1 (0.56) DAOLMNAHTTGRIA1GRIA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118047727-A Method for preparing quinoxaline-2, 3-diketone compound by virtue of regioselective photocatalytic oxidation 浙江工业大学台州研究院 2024-05-17 CN disclosed