SCHEMBL7329647

SCHEMBL7329647

O=c1[nH]c2ccccc2n(Cc2ccccc2)c1=O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APOBEC3G Q9HC16 1/20 0.61
LMNA P02545 1/20 0.60
HTT P42858 1/20 0.60
GRIA1 P42261 2/20 0.57
GRIA2 P42262 2/20 0.57
GRIA3 P42263 2/20 0.57
GRIA4 P48058 2/20 0.57
KDM4E B2RXH2 2/20 0.55
ALDH1A1 P00352 2/20 0.55
HPGD P15428 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
CYP1A2 P05177 1/20 0.51
PARP1 P09874 1/20 0.49
P2RX4 Q99571 1/20 0.49
CFTR P13569 1/20 0.47
POLB P06746 2/20 0.46
RECQL P46063 1/20 0.46
CASP6 P55212 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30530478 1.00 APOBEC3G (0.61) APOBEC3GLMNAHTTGRIA1GRIA2
SCHEMBL30898292 0.85 GRIA1 (0.56) APOBEC3GLMNAHTTGRIA1GRIA2
SCHEMBL7318966 0.85 GRIA1 (0.56) APOBEC3GLMNAHTTGRIA1GRIA2
SCHEMBL30898291 0.85 GRIA1 (0.56) APOBEC3GLMNAHTTGRIA1GRIA2
SCHEMBL2762074 0.84 LMNA (0.81) APOBEC3GLMNAHTTKDM4EALDH1A1
SCHEMBL7321461 0.84 KDM4E (0.67) LMNAHTTGRIA1GRIA2GRIA3
SCHEMBL29579885 0.83 CYP1A2 (0.69) HTTGRIA1GRIA2GRIA3GRIA4
SCHEMBL982104 0.83 CYP1A2 (0.69) HTTGRIA1GRIA2GRIA3GRIA4
SCHEMBL10508287 0.82 PARG (0.53) LMNAHTTGRIA1GRIA2GRIA3
SCHEMBL30898293 0.82 DAO (0.50) APOBEC3GLMNAHTTGRIA1GRIA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118047727-A Method for preparing quinoxaline-2, 3-diketone compound by virtue of regioselective photocatalytic oxidation 浙江工业大学台州研究院 2024-05-17 CN disclosed
US-5075304-A Nervous system disorders NOVO NORDISK A/S (DK) 1991-12-24 US disclosed
EP-0344943-A1 Imidazoquinoxaline compounds and their preparation and use NOVO NORDISK A/S (DK) 1989-12-06 EP disclosed