SCHEMBL30898303

SCHEMBL30898303

O=C1Nc2ccccc2C1=Cc1ccc[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 10/20 1.00
TLK2 Q86UE8 6/20 1.00
PDGFRB P09619 5/20 1.00
KDR P35968 4/20 1.00
RET P07949 4/20 1.00
FLT3 P36888 3/20 1.00
JAK3 P52333 3/20 1.00
FLT1 P17948 2/20 1.00
ALK Q9UM73 2/20 1.00
CDK5 Q00535 2/20 1.00
AURKB Q96GD4 2/20 1.00
SYK P43405 1/20 1.00
ATM Q13315 1/20 1.00
CHEK1 O14757 1/20 1.00
AURKA O14965 1/20 1.00
DAPK3 O43293 1/20 1.00
PRKD3 O94806 1/20 1.00
MAP4K4 O95819 1/20 1.00
NTRK1 P04629 1/20 1.00
LCK P06239 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1162656 1.00 PDPK1 (1.00) PDPK1TLK2PDGFRBKDRRET
SCHEMBL30898301 1.00 PDPK1 (1.00) PDPK1TLK2PDGFRBKDRRET
SCHEMBL29385385 1.00 PDPK1 (1.00) PDPK1TLK2PDGFRBKDRRET
SCHEMBL1162655 1.00 PDPK1 (1.00) PDPK1TLK2PDGFRBKDRRET
SCHEMBL13038796 1.00 PDPK1 (1.00) PDPK1TLK2PDGFRBKDRRET
SCHEMBL32676559 0.85 PDPK1 (0.74) PDPK1TLK2PDGFRBKDRRET
SCHEMBL32676535 0.85 PDPK1 (0.74) PDPK1TLK2PDGFRBKDRRET
SCHEMBL32676572 0.85 PDPK1 (0.74) PDPK1TLK2PDGFRBKDRRET
SCHEMBL7819649 0.82 PDPK1 (0.68) PDPK1TLK2PDGFRBKDRRET
SCHEMBL7819646 0.82 PDPK1 (0.68) PDPK1TLK2PDGFRBKDRRET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4611814-A1 IN VIVO TARGETING OF THERAPEUTIC MOLECULES TO THE RETINA VIA THE OPTICAL SYSTEM OF THE EYE Semmelweis Egyetem (HU) 2025-09-10 EP disclosed
WO-2024095026-A1 IN VIVO TARGETING OF THERAPEUTIC MOLECULES TO THE RETINA VIA THE OPTICAL SYSTEM OF THE EYE SEMMELWEIS EGYETEM (HU) 2024-05-10 WO disclosed