Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 10/20 | 1.00 |
| ▸ | TLK2 | Q86UE8 | 6/20 | 1.00 |
| ▸ | PDGFRB | P09619 | 5/20 | 1.00 |
| ▸ | KDR | P35968 | 4/20 | 1.00 |
| ▸ | RET | P07949 | 4/20 | 1.00 |
| ▸ | FLT3 | P36888 | 3/20 | 1.00 |
| ▸ | JAK3 | P52333 | 3/20 | 1.00 |
| ▸ | FLT1 | P17948 | 2/20 | 1.00 |
| ▸ | ALK | Q9UM73 | 2/20 | 1.00 |
| ▸ | CDK5 | Q00535 | 2/20 | 1.00 |
| ▸ | AURKB | Q96GD4 | 2/20 | 1.00 |
| ▸ | SYK | P43405 | 1/20 | 1.00 |
| ▸ | ATM | Q13315 | 1/20 | 1.00 |
| ▸ | CHEK1 | O14757 | 1/20 | 1.00 |
| ▸ | AURKA | O14965 | 1/20 | 1.00 |
| ▸ | DAPK3 | O43293 | 1/20 | 1.00 |
| ▸ | PRKD3 | O94806 | 1/20 | 1.00 |
| ▸ | MAP4K4 | O95819 | 1/20 | 1.00 |
| ▸ | NTRK1 | P04629 | 1/20 | 1.00 |
| ▸ | LCK | P06239 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30898303 | 1.00 | PDPK1 (1.00) | PDPK1TLK2PDGFRBKDRRET | |
| SCHEMBL1162656 | 1.00 | PDPK1 (1.00) | PDPK1TLK2PDGFRBKDRRET | |
| SCHEMBL30898301 | 1.00 | PDPK1 (1.00) | PDPK1TLK2PDGFRBKDRRET | |
| SCHEMBL1162655 | 1.00 | PDPK1 (1.00) | PDPK1TLK2PDGFRBKDRRET | |
| SCHEMBL13038796 | 1.00 | PDPK1 (1.00) | PDPK1TLK2PDGFRBKDRRET | |
| SCHEMBL32676559 | 0.85 | PDPK1 (0.74) | PDPK1TLK2PDGFRBKDRRET | |
| SCHEMBL32676535 | 0.85 | PDPK1 (0.74) | PDPK1TLK2PDGFRBKDRRET | |
| SCHEMBL32676572 | 0.85 | PDPK1 (0.74) | PDPK1TLK2PDGFRBKDRRET | |
| SCHEMBL7819649 | 0.82 | PDPK1 (0.68) | PDPK1TLK2PDGFRBKDRRET | |
| SCHEMBL7819646 | 0.82 | PDPK1 (0.68) | PDPK1TLK2PDGFRBKDRRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112175041-B | Ethyl QRPAK modified bis-carbolino piperazine diketone and preparation, activity and application thereof | 首都医科大学（CN） | 2023-01-13 | — | — | CN | claimed |
| CN-114763355-A | Heptacyclic indole diketopiperazine compound, preparation, antithrombotic activity and application thereof | 首都医科大学 | 2022-07-19 | — | — | CN | claimed |
| CN-114763354-A | Heptacyclo indole diketopiperazine non-covalent bond trimer, preparation, thrombolytic activity and application thereof | 首都医科大学 | 2022-07-19 | — | — | CN | claimed |
| EP-4715066-A1 | PANEL OF MICRORNAS AS BIOMARKERS OF NON-SEGMENTAL VITILIGO | Servicio Andaluz De Salud (ES) | 2026-03-25 | — | — | EP | disclosed |
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| US-12312642-B2 | Method for the diagnosis, prognosis and treatment of breast cancer metastasis | FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA) (ES) | 2025-05-27 | — | — | US | disclosed |
| US-20250161459-A1 | TRKB LIGAND CONJUGATED COMPOUNDS AND USES THEREOF | ADARX PHARMACEUTICALS, INC. (US) | 2025-05-22 | — | — | US | disclosed |
| US-20250115912-A1 | METHOD FOR THE DIAGNOSIS, PROGNOSIS AND TREATMENT OF CANCER METASTASIS | FUNDACIO INST DE RECERCA BIOMEDICA IRB BARCELONA (ES) | 2025-04-10 | — | — | US | disclosed |
| US-20250078957-A1 | Unsupervised Machine Learning Methods | AMPEL BIOSOLUTIONS LLC (US) | 2025-03-06 | — | — | US | disclosed |
| US-20250022541-A1 | Unsupervised Machine Learning Methods | AMPEL BIOSOLUTIONS LLC (US) | 2025-01-16 | — | — | US | disclosed |
| US-12196758-B2 | Method for the prognosis and treatment of cancer metastasis | FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA) and INSTITUCIO CATALANA DE RECERCA I ESTUDIS AVANCATS (ES) | 2025-01-14 | — | — | US | disclosed |
| WO-2023158713-A1 | UNSUPERVISED MACHINE LEARNING METHODS | AMPEL BIOSOLUTIONS, LLC (US) | 2023-08-24 | — | — | WO | disclosed |
| CN-114763354-B | Heptacycloindole diketopiperazine non-covalent bond trimer, preparation, thrombolytic activity and application thereof | 首都医科大学 | 2023-05-05 | — | — | CN | disclosed |
| US-11591599-B2 | Method for the diagnosis, prognosis and treatment of cancer metastasis | FUNDACIÓ INSTITUT DE RECERCA BIOMÈDICA (IRB BARCELONA) (ES) | 2023-02-28 | — | — | US | disclosed |
| CN-112175041-B | Ethyl QRPAK modified bis-carbolino piperazine diketone and preparation, activity and application thereof | 首都医科大学（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-110577582-B | LDV modified heptacyclic aldehyde, synthesis, antithrombotic activity and application thereof | 首都医科大学 | 2022-09-02 | — | — | CN | disclosed |
| US-11352673-B2 | Method for the diagnosis, prognosis and treatment of lung cancer metastasis | FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA) | 2022-06-07 | — | — | US | disclosed |
| US-11318138-B2 | Methods for treating B cell proliferative disorders | CORNELL UNIVERSITY (US) | 2022-05-03 | — | — | US | disclosed |
| US-20220049316-A1 | METHOD FOR THE DIAGNOSIS, PROGNOSIS AND TREATMENT OF BREAST CANCER METASTASIS | FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA) (ES) | 2022-02-17 | — | — | US | disclosed |
| US-20220042997-A1 | METHOD FOR THE DIAGNOSIS, PROGNOSIS AND TREATMENT OF PROSTATE CANCER METASTASIS | INBIOMOTION S.L. (ES) | 2022-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11318138-B2 | Methods for treating B cell proliferative disorders | CDK4, BCL6, BCL6B | PDPK1 286/4885TLK2 1220/4885PDGFRB 481/4885 |
| US-20220042997-A1 | METHOD FOR THE DIAGNOSIS, PROGNOSIS AND TREATMENT OF PROSTATE CANCER METASTASIS | MAFG, MAFK, ACP3 | PDPK1 3896/4885TLK2 3667/4885PDGFRB 1505/4885 |
| US-12196758-B2 | Method for the prognosis and treatment of cancer metastasis | MAFG, BRCA1, BCOR | PDPK1 4611/4885TLK2 2500/4885PDGFRB 498/4885 |
| US-20250161459-A1 | TRKB LIGAND CONJUGATED COMPOUNDS AND USES THEREOF | NTRK2, NTRK1, BDNF | PDPK1 1465/4885TLK2 488/4885PDGFRB 95/4885 |
| US-11591599-B2 | Method for the diagnosis, prognosis and treatment of cancer metastasis | MAFG, RHOXF2, MAFK | PDPK1 3495/4885TLK2 2060/4885PDGFRB 1080/4885 |
| US-20220049316-A1 | METHOD FOR THE DIAGNOSIS, PROGNOSIS AND TREATMENT OF BREAST CANCER METASTASIS | MAFG, MAFK, CRACR2A | PDPK1 3821/4885TLK2 3893/4885PDGFRB 1794/4885 |
| US-20250115912-A1 | METHOD FOR THE DIAGNOSIS, PROGNOSIS AND TREATMENT OF CANCER METASTASIS | MAFG, RHOXF2, MAFK | PDPK1 3495/4885TLK2 2060/4885PDGFRB 1080/4885 |
| US-11352673-B2 | Method for the diagnosis, prognosis and treatment of lung cancer metastasis | MAFG, MAFK, MYCBP | PDPK1 3895/4885TLK2 2732/4885PDGFRB 1568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.