Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25145868 | 1.00 | KDM4E (0.46) | KDM4ELMNAABL1MAPTSMN1; SMN2 | |
| SCHEMBL31239676 | 0.80 | HSD17B10 (0.40) | SMN1; SMN2HPGDALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL20798102 | 0.80 | AVPR1A (0.44) | HPGDALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL485461 | 0.79 | KCNH2 (0.48) | KDM4ELMNAABL1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL25309482 | 0.78 | HSD17B10 (0.39) | SMN1; SMN2HPGDALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL25145697 | 0.77 | PARP1 (0.38) | HPGDALDH1A1CYP1A2EIF2AK4 | |
| SCHEMBL231823 | 0.76 | ADRB1 (0.60) | KDM4ELMNAABL1MAPTSMN1; SMN2 | |
| SCHEMBL20511824 | 0.76 | GRIN2D (0.44) | HPGDALDH1A1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL17035908 | 0.76 | ADRB1 (0.60) | KDM4ELMNAABL1MAPTSMN1; SMN2 | |
| SCHEMBL31541438 | 0.76 | GRIN2D (0.44) | HPGDALDH1A1CYP3A4CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118103374-A | Heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2024-05-28 | — | — | CN | disclosed |