Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ABL1 | P00519 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.49 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30101389 | 1.00 | ADRB1 (0.60) | ADRB1KDM4ELMNAABL1MAPT | |
| SCHEMBL231823 | 1.00 | ADRB1 (0.60) | ADRB1KDM4ELMNAABL1MAPT | |
| Hydrochloric Acid SCHEMBL9530917 | 0.98 | ADRB1 (0.59) | ADRB1KDM4ELMNAABL1MAPT | |
| Hydrochloric Acid SCHEMBL9394896 | 0.98 | ADRB1 (0.59) | ADRB1KDM4ELMNAABL1MAPT | |
| SCHEMBL30567235 | 0.94 | ADRB1 (0.55) | ADRB1KDM4ELMNAABL1MAPT | |
| SCHEMBL2155294 | 0.94 | ADRB1 (0.55) | ADRB1KDM4ELMNAABL1MAPT | |
| Hydrochloric Acid SCHEMBL2120987 | 0.93 | ADRB1 (0.54) | ADRB1KDM4ELMNAABL1MAPT | |
| SCHEMBL1742865 | 0.88 | GPR119 (0.57) | ADRB1KDM4ELMNAABL1ADRB2 | |
| SCHEMBL15316690 | 0.87 | ADRB1 (0.50) | ADRB1KDM4ELMNAABL1MAPT | |
| SCHEMBL6809004 | 0.85 | GAA (0.60) | KDM4ELMNAABL1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150239796-A1 | ONE POT SYNTHESIS OF 18F LABELEDTRIFLUOROMETHYLATED COMPOUNDS WITH DIFLUORO(IODO)METHANE | UNIVERSITY OF OSLO (NO) | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239796-A1 | ONE POT SYNTHESIS OF 18F LABELEDTRIFLUOROMETHYLATED COMPOUNDS WITH DIFLUORO(IODO)METHANE | FLI1, AFF1, CYP2F1 | ADRB1 2133/4885KDM4E 1321/4885LMNA 4820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.