Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22717380 | 1.00 | KDM4E (0.50) | KDM4EALDH1A1LMNATP53MAPT | |
| SCHEMBL31167806 | 0.87 | DPP4 (0.50) | DPP4 | |
| SCHEMBL22717275 | 0.87 | POLB (0.48) | KDM4EALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL29574145 | 0.86 | ALDH1A1 (0.47) | KDM4EALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL22717493 | 0.86 | ALDH1A1 (0.47) | KDM4EALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL5778875 | 0.86 | ALDH1A1 (0.53) | KDM4EALDH1A1LMNATP53MAPT | |
| SCHEMBL22717735 | 0.85 | DPP4 (0.49) | ALDH1A1LMNATP53MAPTMEN1 | |
| SCHEMBL22717257 | 0.84 | MAPT (0.47) | LMNATP53MAPTMEN1KMT2A | |
| SCHEMBL22717520 | 0.84 | GABRP (0.51) | LMNATP53MAPTMEN1KMT2A | |
| SCHEMBL22717321 | 0.84 | MAPT (0.47) | LMNATP53MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118055930-A | Thiadiazole derivative, composition and application thereof | 北京丹擎医药科技有限公司 | 2024-05-17 | — | — | CN | disclosed |