SCHEMBL30898569

SCHEMBL30898569

CCOC(=O)c1c[nH]c2ccc(I)cc2c1=O

nearest known ligand 0.74

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.74
GABRB2 P47870 4/20 0.74
GABRB1 P18505 3/20 0.73
GABRA3 P34903 3/20 0.73
MEN1 O00255 1/20 0.64
ALDH1A1 P00352 1/20 0.64
TP53 P04637 1/20 0.64
HPGD P15428 1/20 0.64
KMT2A Q03164 1/20 0.64
HSD17B10 Q99714 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
CLEC4M Q9H2X3 1/20 0.55
CYP1A2 P05177 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2C19 P33261 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1211778 1.00 GABRA1 (0.74) GABRA1GABRB2GABRB1GABRA3MEN1
SCHEMBL27774056 0.90 GABRA1 (0.60) GABRA1GABRB2GABRB1GABRA3MEN1
SCHEMBL1430520 0.90 GABRA1 (0.63) GABRA1GABRB2GABRB1GABRA3MEN1
SCHEMBL7284420 0.86 GABRA1 (0.78) GABRA1GABRB2GABRB1GABRA3MEN1
SCHEMBL30417619 0.86 GABRA1 (0.78) GABRA1GABRB2GABRB1GABRA3MEN1
SCHEMBL7291769 0.85 GABRA1 (1.00) GABRA1GABRB2GABRB1GABRA3MEN1
SCHEMBL7381114 0.84 GABRA1 (1.00) GABRA1GABRB2GABRB1GABRA3MEN1
SCHEMBL22886423 0.84 GABRA1 (0.74) GABRA1GABRB2GABRB1GABRA3MEN1
SCHEMBL846416 0.84 GABRA1 (0.74) GABRA1GABRB2GABRB1GABRA3MEN1
SCHEMBL1366633 0.84 GABRA1 (0.74) GABRA1GABRB2GABRB1GABRA3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119306697-A 4-Quinolinone derivative and preparation method and application thereof 山东大学 2025-01-14 CN disclosed
CN-117924169-A Dihydroquinoline derivative and pharmaceutical application thereof in resisting influenza 山东大学齐鲁医院 2024-04-26 CN disclosed