Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5859401 | 0.95 | TSHR (0.56) | TSHRALDH1A1TDP1LMNACYP3A4 | |
| SCHEMBL25181783 | 0.93 | TSHR (0.56) | TSHRALDH1A1TDP1LMNACYP3A4 | |
| SCHEMBL9718823 | 0.93 | TSHR (0.54) | TSHRALDH1A1LMNACYP3A4 | |
| SCHEMBL9718866 | 0.91 | TSHR (0.60) | TSHRALDH1A1LMNA | |
| SCHEMBL25185574 | 0.91 | TSHR (0.60) | TSHRALDH1A1LMNA | |
| SCHEMBL25182455 | 0.91 | TSHR (0.58) | TSHRALDH1A1LMNACYP3A4 | |
| SCHEMBL25172412 | 0.91 | TSHR (0.58) | TSHRALDH1A1LMNACYP3A4 | |
| SCHEMBL25182470 | 0.91 | TSHR (0.58) | TSHRALDH1A1LMNACYP3A4 | |
| SCHEMBL25178043 | 0.91 | TSHR (0.50) | TSHRALDH1A1TDP1CYP3A4 | |
| SCHEMBL1907970 | 0.90 | TSHR (0.62) | TSHRALDH1A1TDP1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981859-B1 | PREPARATION OF DELMOPINOL | SINCLAIR PHARMACEUTICALS LTD (GB) | 2012-10-31 | — | — | EP | disclosed |
| US-8093398-B2 | Preparation of delmopinol | Sinclair Pharmaceticals Limited (GB) | 2012-01-10 | — | — | US | disclosed |
| US-20110082301-A1 | Preparation of Delmopinol | COMELY ALEXANDER | 2011-04-07 | — | — | US | disclosed |
| US-7893258-B2 | Preparation of delmopinol | SINCLAIR PHARMACEUTICALS LIMITED (GB) | 2011-02-22 | — | — | US | disclosed |
| US-20090036677-A1 | Preparation of Delmopinol | MAELOR LABORATORIES LIMITED (GB) | 2009-02-05 | — | — | US | disclosed |
| EP-1981859-A2 | PREPARATION OF DELMOPINOL | Sinclair Pharmaceuticals Limited (GB) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007091009-A2 | PREPARATION OF DELMOPINOL | SINCLAIR PHARMACEUTICALS LIMITED (GB) | 2007-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110082301-A1 | Preparation of Delmopinol | CBR3, AVPR2, C1S | TSHR 466/4885ALDH1A1 2640/4885TDP1 4424/4885 |
| US-20090036677-A1 | Preparation of Delmopinol | AVPR2, CBR3, C1S | TSHR 395/4885ALDH1A1 2718/4885TDP1 4465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.