SCHEMBL5859401

SCHEMBL5859401

C=CCCCC(CCC)CCCC

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.56
ALDH1A1 P00352 4/20 0.56
TDP1 Q9NUW8 1/20 0.38
CYP3A4 P08684 2/20 0.37
LMNA P02545 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
DNM1 Q05193 2/20 0.32
CA2 P00918 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
PLA2G2C Q5R387 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1907970 0.95 TSHR (0.62) TSHRALDH1A1TDP1CYP3A4LMNA
SCHEMBL308987 0.95 TSHR (0.55) TSHRALDH1A1TDP1CYP3A4LMNA
SCHEMBL25178030 0.93 TSHR (0.56) TSHRALDH1A1TDP1CYP3A4LMNA
SCHEMBL25181783 0.93 TSHR (0.56) TSHRALDH1A1TDP1CYP3A4LMNA
SCHEMBL9718866 0.91 TSHR (0.60) TSHRALDH1A1LMNADNM1PLA2G2C
SCHEMBL25172413 0.91 TSHR (0.60) TSHRALDH1A1TDP1CYP3A4LMNA
SCHEMBL25182423 0.91 TSHR (0.60) TSHRALDH1A1TDP1CYP3A4LMNA
SCHEMBL25185574 0.91 TSHR (0.60) TSHRALDH1A1LMNADNM1PLA2G2C
SCHEMBL25178838 0.91 TSHR (0.50) TSHRALDH1A1TDP1CYP3A4LMNA
SCHEMBL25178120 0.91 TSHR (0.58) TSHRALDH1A1TDP1CYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE31812-E TO ALDEHYDES IN PRESENCE OF CATALYTIC SYSTEM CONTAINING RHODIUM AND SULFONATED ARYL PHOSPHINE COMPOUND RHONE-POULENC INDUSTRIES (FR) 1985-01-22 US claimed
US-4248802-A Catalytic hydroformylation of olefins RHONE-POULENC INDUSTRIES (FR) 1981-02-03 US claimed
CN-118201905-A Cationic lipid 武田药品工业株式会社 2024-06-14 CN disclosed
WO-2023085299-A1 CATIONIC LIPID 武田薬品工業株式会社 2023-05-19 WO disclosed
US-6995293-B2 Method for the production of aldehydes CELANESE CHEMICALS EUROPE GMBH (DE) 2006-02-07 US disclosed
US-20050085671-A1 Method for the production of aldehydes DRACHENFELSSEE 521. VV GMBH (TO BE RENAMED OXEA DEUTSCHLAND GMBH) (DE) 2005-04-21 US disclosed
EP-1390334-A2 HYDROFORMYLATION PROCESS Davy Process Technology Limited (GB) 2004-02-25 EP disclosed
US-20020188160-A1 The catalyst either water-soluble or carbon dioxide-soluble and the reaction product soluble in the phase in which the catalyst is insoluble, wherein the reaction products and catalyst can be readily separated by a phase separation LOS ALAMOS NATIONAL SECURITY, LLC 2002-12-12 US disclosed
WO-2002096848-A2 HYDROFORMYLATION PROCESS DAVY PROCESS TECHNOLOGY LIMITED (GB) 2002-12-05 WO disclosed
US-6479708-B1 The catalyst either water-soluble or carbon dioxide-soluble and the reaction product soluble in the phase in which the catalyst is insoluble, wherein the reaction products and catalyst can be readily separated by a phase separation THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2002-11-12 US disclosed
US-6472565-B1 Method for producing aldehydes CELANESE CHEMICALS EUROPE GMBH (DE) 2002-10-29 US disclosed
US-5118867-A Hydroformylation of an definically unsaturated compound, rhodium catalyst, a soluble ammonium salt of a sulfonated phosphorous acid triester HOECHST AKTIENGESELLSCHAFT (DE) 1992-06-02 US disclosed
US-5093297-A Polystyrene immobilized rhodium complex catalyst for the hydroformylation of olefins KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1992-03-03 US disclosed
EP-0435084-A1 Process for the production of aldehydes HOECHST AKTIENGESELLSCHAFT (DE) 1991-07-03 EP disclosed
US-4889957-A HYDROFORMYLATION OF UNSATURATED HYDROCARBONS RHONE-POULENC CHIMIE DE BASE (FR) 1989-12-26 US disclosed
US-4778905-A WITH SULFONATED TRIARYLPHOSPHINE LIGAND RHONE-POULENC CHIMIE DE BASE (FR) 1988-10-18 US disclosed
US-RE31812-E TO ALDEHYDES IN PRESENCE OF CATALYTIC SYSTEM CONTAINING RHODIUM AND SULFONATED ARYL PHOSPHINE COMPOUND RHONE-POULENC INDUSTRIES (FR) 1985-01-22 US disclosed
EP-0096987-A2 Hydroformylation process DAVY McKEE (LONDON) LIMITED (GB) 1983-12-28 EP disclosed
EP-0096986-A2 Hydroformylation process DAVY McKEE (LONDON) LIMITED (GB) 1983-12-28 EP disclosed
US-4248802-A Catalytic hydroformylation of olefins RHONE-POULENC INDUSTRIES (FR) 1981-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020188160-A1 The catalyst either water-soluble or carbon dioxide-soluble and the reaction product soluble in the phase in which the catalyst is insoluble, wherein the reaction products and catalyst can be readily separated by a phase separation MED1, CD14, AP2S1 TSHR 2599/4885ALDH1A1 4295/4885TDP1 3506/4885
US-20050085671-A1 Method for the production of aldehydes ACSL3, ACSL5, TST TSHR 3705/4885ALDH1A1 116/4885TDP1 4189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.