Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30898770 | 0.95 | MAPT (0.56) | HSD17B10HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL14744565 | 0.89 | ALDH1A1 (0.66) | ALDH1A1CA1CA2PSIP1FFAR1 | |
| SCHEMBL30898784 | 0.82 | IDO1 (0.47) | SMN1; SMN2ALDH1A1PSIP1KDM4EHPGD | |
| SCHEMBL19248976 | 0.81 | HDAC1 (0.65) | HSD17B10HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL6208836 | 0.81 | SMN1; SMN2 (0.82) | HSD17B10HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL27643053 | 0.81 | SMN1; SMN2 (0.58) | HSD17B10HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL30026758 | 0.80 | CA2 (0.65) | SMN1; SMN2ALDH1A1CA1CA2PSIP1 | |
| SCHEMBL80973 | 0.80 | HSD17B10 (0.67) | HSD17B10HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL765942 | 0.80 | HSD17B10 (0.67) | HSD17B10HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL10482320 | 0.80 | HSD17B10 (0.71) | HSD17B10HDAC3MAPK1ADRA1AHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113072542-B | ROR gamma t inhibitor and preparation method and application thereof | 广东东阳光药业股份有限公司 | 2024-04-05 | — | — | CN | disclosed |