Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 6/20 | 0.41 |
| ▸ | GPR52 | Q9Y2T5 | 5/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17592697 | 0.79 | GPR52 (0.57) | GPR52 | |
| SCHEMBL28570960 | 0.79 | GPR52 (0.47) | KMT2AGPR52 | |
| SCHEMBL13971097 | 0.79 | GPR52 (0.61) | ALDH1A1KMT2AHTTGPR52CNR1 | |
| SCHEMBL17592695 | 0.79 | GPR52 (0.57) | GPR52 | |
| SCHEMBL5972763 | 0.79 | GPR52 (0.60) | GPR52 | |
| SCHEMBL7374431 | 0.79 | GPR52 (0.60) | GPR52 | |
| SCHEMBL25136593 | 0.75 | KMT2A (0.52) | ALDH1A1KMT2ARORC | |
| SCHEMBL30898772 | 0.74 | IDO1 (0.56) | PSIP1ALDH1A1LMNARAB9ANPSR1 | |
| SCHEMBL13859132 | 0.73 | PSIP1 (0.55) | PSIP1ALDH1A1KMT2ATP53TSHR | |
| SCHEMBL30898784 | 0.72 | IDO1 (0.47) | PSIP1ALDH1A1KMT2ARAB9ARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113072542-B | ROR gamma t inhibitor and preparation method and application thereof | 广东东阳光药业股份有限公司 | 2024-04-05 | — | — | CN | disclosed |