Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | GAA | P10253 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30899182 | 0.79 | MAPT (0.44) | CYP1A2CYP3A4MAPTNPSR1MEN1 | |
| SCHEMBL30899178 | 0.72 | MAPT (0.56) | CYP1A2CYP3A4MAPTMEN1HTT | |
| SCHEMBL30899179 | 0.72 | MAPT (0.56) | CYP1A2CYP3A4MAPTMEN1HTT | |
| SCHEMBL11226669 | 0.68 | ALDH1A1 (0.74) | CYP1A2CYP3A4MAPTNPSR1MEN1 | |
| SCHEMBL11486327 | 0.68 | ALDH1A1 (0.74) | CYP1A2CYP3A4MAPTNPSR1MEN1 | |
| SCHEMBL30197946 | 0.68 | CYP1A2 (0.68) | CYP1A2CYP3A4MAPTNPSR1MEN1 | |
| SCHEMBL13380954 | 0.68 | MAPT (1.00) | CYP1A2CYP3A4MAPTNPSR1MEN1 | |
| SCHEMBL30899183 | 0.67 | NPC1 (0.45) | CYP1A2CYP3A4MAPTNPSR1MEN1 | |
| SCHEMBL22925149 | 0.66 | L3MBTL1 (0.62) | CYP1A2CYP3A4MAPTNPSR1MEN1 | |
| SCHEMBL11495662 | 0.65 | MAPT (1.00) | CYP1A2CYP3A4MAPTNPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240294536-A1 | FUSED TRIAZOLO-PYRIMIDINE COMPOUNDS HAVING USEFUL PHARMACEUTICAL APPLICATION | PIKSCI INC. (CA) | 2024-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240294536-A1 | FUSED TRIAZOLO-PYRIMIDINE COMPOUNDS HAVING USEFUL PHARMACEUTICAL APPLICATION | PIKFYVE, PIP4K2B, PIK3CA | CYP1A2 4479/4885CYP3A4 2973/4885MAPT 3840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.