Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | CRBN | Q96SW2 | 7/20 | 0.60 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.60 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.54 |
| ▸ | HTR3A | P46098 | 2/20 | 0.54 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.53 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.53 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.51 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 2/20 | 0.51 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.51 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19359344 | 1.00 | NPC1 (0.60) | NPC1RAB9ACRBNDDB1CNR1 | |
| SCHEMBL19370714 | 1.00 | NPC1 (0.60) | NPC1RAB9ACRBNDDB1CNR1 | |
| SCHEMBL23413562 | 0.83 | CRBN (0.60) | CRBNDDB1IKZF3BRD4 | |
| SCHEMBL26715308 | 0.80 | NPC1 (0.67) | NPC1RAB9ACNR1CNR2CHRNA7 | |
| SCHEMBL20812420 | 0.78 | DDB1 (0.59) | CRBNDDB1 | |
| SCHEMBL20779009 | 0.77 | CRBN (0.62) | CRBNDDB1CNR2IKZF3BRD4 | |
| SCHEMBL20775426 | 0.77 | CRBN (0.62) | CRBNDDB1CNR2IKZF3BRD4 | |
| SCHEMBL20774154 | 0.77 | CRBN (0.62) | CRBNDDB1CNR2IKZF3BRD4 | |
| SCHEMBL30899453 | 0.77 | CRBN (0.62) | CRBNDDB1CNR2IKZF3BRD4 | |
| SCHEMBL30899433 | 0.77 | CRBN (0.62) | CRBNDDB1CNR2IKZF3BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108706-A | Glutarimide | C4医药公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-111278815-B | Glutarimide | C4医药公司 | 2024-03-08 | — | — | CN | disclosed |