Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19586797 | 0.83 | CRBN (0.59) | DDB1CRBN | |
| SCHEMBL19586378 | 0.83 | CRBN (0.59) | DDB1CRBN | |
| SCHEMBL19586490 | 0.79 | CRBN (0.44) | DDB1CRBN | |
| SCHEMBL20812609 | 0.78 | MAPK10 (0.40) | — | |
| SCHEMBL19370714 | 0.78 | NPC1 (0.60) | DDB1CRBN | |
| SCHEMBL19359344 | 0.78 | NPC1 (0.60) | DDB1CRBN | |
| SCHEMBL30899435 | 0.78 | NPC1 (0.60) | DDB1CRBN | |
| SCHEMBL21965481 | 0.75 | DDB1 (1.00) | DDB1CRBN | |
| SCHEMBL21965879 | 0.74 | DDB1 (0.56) | DDB1CRBN | |
| SCHEMBL20805224 | 0.74 | DDB1 (0.58) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190076539-A1 | AMINE-LINKED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION | C4 Theraprutics, Inc. (US) | 2019-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190076539-A1 | AMINE-LINKED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION | GCGR, STUB1, GID4 | DDB1 503/4885CRBN 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.