Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 3/20 | 0.40 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | BCDIN3D | Q7Z5W3 | 4/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23872469 | 0.81 | PDE2A (0.42) | PDE2AHTR2CMEN1KMT2AHRH1 | |
| SCHEMBL29786789 | 0.78 | KMT2A (0.40) | PDE2AHTR2CMEN1KMT2AHRH1 | |
| SCHEMBL30935932 | 0.78 | PDE2A (0.40) | PDE2AHTR2CMEN1KMT2AHRH1 | |
| SCHEMBL29133371 | 0.78 | PDE2A (0.47) | PDE2AMEN1KMT2AKCNH2TLR8 | |
| SCHEMBL24654997 | 0.78 | KMT2A (0.41) | PDE2AHTR2CMEN1KMT2AHRH1 | |
| SCHEMBL20674220 | 0.78 | PDE2A (0.40) | PDE2AHTR2CMEN1KMT2AHRH1 | |
| SCHEMBL19953294 | 0.78 | KMT2A (0.40) | PDE2AHTR2CMEN1KMT2AHRH1 | |
| SCHEMBL2737319 | 0.75 | S1PR2 (0.45) | PDE2AMEN1KMT2AHRH1HRH4 | |
| SCHEMBL15024697 | 0.73 | KDM4E (0.43) | PDE2AMEN1KMT2ATP53F7 | |
| SCHEMBL15024702 | 0.73 | KDM4E (0.54) | KMT2AF7F3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076604-A | Pyrazolo [3,4-b ] pyridine compounds for the treatment of autoimmune diseases | 豪夫迈·罗氏有限公司 | 2024-05-24 | — | — | CN | disclosed |