Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.37 |
| ▸ | PI4KA | P42356 | 1/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20674220 | 1.00 | PDE2A (0.40) | PDE2AGAAKMT2AMEN1KCNH2 | |
| SCHEMBL23872469 | 0.81 | PDE2A (0.42) | PDE2AGAAKMT2AMEN1KCNH2 | |
| SCHEMBL31749126 | 0.80 | PDE2A (0.46) | PDE2AGAAKMT2AMEN1PI4KA | |
| SCHEMBL31749125 | 0.80 | PDE2A (0.46) | PDE2AGAAKMT2AMEN1PI4KA | |
| SCHEMBL30899643 | 0.78 | PDE2A (0.40) | PDE2AKMT2AMEN1KCNH2TLR8 | |
| SCHEMBL29786789 | 0.78 | KMT2A (0.40) | PDE2AGAAKMT2AMEN1KCNH2 | |
| SCHEMBL24654997 | 0.78 | KMT2A (0.41) | PDE2AGAAKMT2AMEN1KCNH2 | |
| SCHEMBL19953294 | 0.78 | KMT2A (0.40) | PDE2AGAAKMT2AMEN1KCNH2 | |
| SCHEMBL29133371 | 0.78 | PDE2A (0.47) | PDE2AGAAKMT2AMEN1KCNH2 | |
| SCHEMBL19953309 | 0.77 | MAPT (0.48) | KMT2AMEN1KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239959-A | Cyclopropane TLR7 and 8 inhibitor and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-118239926-A | TLR7 and 8 inhibitors, preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-06-25 | — | — | CN | disclosed |