Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.48 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 2/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | EED | O75530 | 1/20 | 0.40 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.40 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.40 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 2/20 | 0.40 |
| ▸ | TGM1 | P22735 | 2/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | F13A1 | P00488 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30365855 | 1.00 | GRM5 (0.48) | GRM5LNPEPBTKPRMT1EED | |
| SCHEMBL30899648 | 0.86 | GRM5 (0.48) | GRM5LNPEPBTKPRMT1EED | |
| SCHEMBL30366090 | 0.86 | GRM5 (0.48) | GRM5LNPEPBTKPRMT1EED | |
| SCHEMBL30365846 | 0.82 | GRM5 (0.44) | GRM5LNPEPBTKTMEM97SIGMAR1 | |
| SCHEMBL30899652 | 0.82 | GRM5 (0.44) | GRM5LNPEPBTKTMEM97SIGMAR1 | |
| SCHEMBL30365847 | 0.79 | GRM5 (0.52) | GRM5LNPEPBTKPRMT1EED | |
| SCHEMBL30899650 | 0.79 | GRM5 (0.52) | GRM5LNPEPBTKPRMT1EED | |
| SCHEMBL32677104 | 0.77 | GRM5 (0.53) | GRM5LNPEPBTKPRMT1EED | |
| SCHEMBL8315932 | 0.75 | MEN1 (0.57) | GRM5LNPEPPRMT1MEN1KMT2A | |
| SCHEMBL169492 | 0.74 | GRM5 (0.48) | GRM5LNPEPPRMT1EEDRBBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076604-A | Pyrazolo [3,4-b ] pyridine compounds for the treatment of autoimmune diseases | 豪夫迈·罗氏有限公司 | 2024-05-24 | — | — | CN | disclosed |