Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 4/20 | 0.44 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | CKS1B | P61024 | 2/20 | 0.43 |
| ▸ | SKP1 | P63208 | 2/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30365846 | 1.00 | GRM5 (0.44) | GRM5GRM1LNPEPGPR119CKS1B | |
| SCHEMBL30366121 | 0.84 | GRM1 (0.52) | GRM5GRM1LNPEPGPR119TMEM97 | |
| SCHEMBL30899634 | 0.84 | GRM1 (0.52) | GRM5GRM1LNPEPGPR119TMEM97 | |
| SCHEMBL30899653 | 0.82 | GRM5 (0.48) | GRM5LNPEPTMEM97SIGMAR1BTK | |
| SCHEMBL30365855 | 0.82 | GRM5 (0.48) | GRM5LNPEPTMEM97SIGMAR1BTK | |
| SCHEMBL30366420 | 0.81 | NAMPT (0.52) | GRM5GRM1LNPEPGPR119TMEM97 | |
| SCHEMBL30366118 | 0.79 | GRM5 (0.51) | GRM5GRM1LNPEPGPR119CKS1B | |
| SCHEMBL30899642 | 0.79 | GRM5 (0.51) | GRM5GRM1LNPEPGPR119CKS1B | |
| SCHEMBL5455714 | 0.74 | NAMPT (0.53) | GRM5GRM1LNPEPGPR119TMEM97 | |
| SCHEMBL5456675 | 0.73 | TMEM97 (0.70) | TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076604-A | Pyrazolo [3,4-b ] pyridine compounds for the treatment of autoimmune diseases | 豪夫迈·罗氏有限公司 | 2024-05-24 | — | — | CN | disclosed |