Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 7/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30899668 | 0.80 | GSK3B (0.44) | SCN9AGSK3BDYRK1ACYP17A1 | |
| SCHEMBL30899678 | 0.77 | KDM4E (0.38) | GSK3BDYRK1AALDH1A1PTGDR2CYP17A1 | |
| SCHEMBL30899677 | 0.73 | GSK3B (0.40) | SCN9AGSK3BDYRK1A | |
| SCHEMBL30899670 | 0.70 | BRD9 (0.39) | SCN9ABRD4GSK3BDYRK1ABRD9 | |
| SCHEMBL13064311 | 0.69 | GSK3B (0.42) | SCN9ABRD4GSK3BDYRK1ABRD9 | |
| SCHEMBL22988880 | 0.68 | LCK (0.41) | GSK3BDYRK1ACYP17A1 | |
| SCHEMBL24517615 | 0.68 | MAPKAPK2 (0.38) | SCN9AGSK3BDYRK1ACYP17A1 | |
| SCHEMBL29394473 | 0.68 | LCK (0.47) | GSK3BDYRK1A | |
| SCHEMBL29498073 | 0.67 | ATR (0.47) | SCN9AGSK3BDYRK1ACYP17A1 | |
| SCHEMBL16925304 | 0.67 | ATR (0.47) | SCN9AGSK3BDYRK1ACYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024067465-A1 | KIF18A INHIBITOR | 山东轩竹医药科技有限公司 | 2024-04-04 | — | — | WO | disclosed |