Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30899677 | 0.81 | GSK3B (0.40) | GSK3BDYRK1ASCN9A | |
| SCHEMBL30899671 | 0.80 | PIM1 (0.39) | GSK3BDYRK1ACYP17A1SCN9A | |
| SCHEMBL30899678 | 0.78 | KDM4E (0.38) | GSK3BDYRK1AMAPK1CYP17A1 | |
| SCHEMBL31017361 | 0.75 | GSK3B (0.37) | GSK3BDYRK1AMAPK1PIK3CDMAPKAPK2 | |
| SCHEMBL25750456 | 0.75 | GSK3B (0.37) | GSK3BDYRK1AMAPK1PIK3CDMAPKAPK2 | |
| SCHEMBL28006554 | 0.73 | GSK3B (0.45) | GSK3BDYRK1ACYP17A1CNR2CACNA1H | |
| SCHEMBL24517615 | 0.71 | MAPKAPK2 (0.38) | GSK3BDYRK1ACYP17A1MAPKAPK2SCN9A | |
| SCHEMBL25833918 | 0.71 | CNR2 (0.38) | GSK3BDYRK1ACYP17A1MAPKAPK2CNR2 | |
| SCHEMBL13064311 | 0.70 | GSK3B (0.42) | GSK3BDYRK1ASCN9A | |
| SCHEMBL29703940 | 0.69 | GSK3B (0.39) | GSK3BDYRK1AMAPK1CYP17A1MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024067465-A1 | KIF18A INHIBITOR | 山东轩竹医药科技有限公司 | 2024-04-04 | — | — | WO | disclosed |